The Human ATP-binding Cassette (ABC) Transporter Superfamily - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Human ATP-binding Cassette (ABC) Transporter Superfamily write by Michael Carlton Dean. This book was released on 2002. The Human ATP-binding Cassette (ABC) Transporter Superfamily available in PDF, EPUB and Kindle.
Plant ABC Transporters
Plant ABC Transporters - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Plant ABC Transporters write by Markus Geisler. This book was released on 2014-09-06. Plant ABC Transporters available in PDF, EPUB and Kindle. This book is devoted to the fascinating superfamily of plant ATP-binding cassette (ABC) transporters and their variety of transported substrates. It highlights their exciting biological functions, covering aspects ranging from cellular detoxification, through development, to symbiosis and defense. Moreover, it also includes a number of chapters that center on ABC transporters from non-Arabidopsis species. ABC proteins are ubiquitous, membrane-intrinsic transporters that catalyze the primary (ATP-dependent) movement of their substrates through biological membranes. Initially identified as an essential aspect of a vacuolar detoxification process, genetic work in the last decade has revealed an unexpectedly diverse variety of ABC transporter substrates, which include not only xenobiotic conjugates, but also heavy metals, lipids, terpenoids, lignols, alkaloids and organic acids. The discovery that members of the ABCB and ABCG family are involved in the movement of phytohormones has further sparked their exploration and provided a new understanding of the whole family. Accordingly, the trafficking, regulation and structure-function of ABCB-type auxin transporters are especially emphasized in this book.
ABC Proteins
ABC Proteins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook ABC Proteins write by I Barry Holland. This book was released on 2003-01-07. ABC Proteins available in PDF, EPUB and Kindle. ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying to stay abreast of the latest findings. This book is sure to become a classic and will regularly be updated. Phylogeny and Evoloution of ABC Transporters Fundamental Aspects of the Mechanism of Action of ABC Transporters Prokaryote ABC Transporters Non-Mammalian Transporters Multidrug Transporters ABC Transporters, Physiological Roles and Human Disease Full color throughout
ABC Transporters - 40 Years on
ABC Transporters - 40 Years on - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook ABC Transporters - 40 Years on write by Anthony M. George. This book was released on 2015-12-16. ABC Transporters - 40 Years on available in PDF, EPUB and Kindle. This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within which chemotherapy failure is observed in about 50% of cases. Together with its complex pharmacology, and even a suspected role in Alzheimer’s disease, this ABC transporter still eludes a clinical solution to its multidrug resistance property. ABC transporters are integral membrane active proteins and they belong to one of the largest protein families across all species. Their myriad roles encompass the import or export of a diverse range of allocrites, including ion, nutrients, peptides, polysaccharides, lipids, and xenobiotics. They are of major medical importance with many members elaborating multidrug resistance in bacteria, fungi, yeast, parasites, and humans. Other ABC transporters are involved in a number of inherited diseases, including cystic fibrosis, macular degeneration, gout, and several other metabolic disorders
Abc Transporters Of Human Physiology And Disease, The: Genetics And Biochemistry Of Atp Binding Cassette Transporters
Abc Transporters Of Human Physiology And Disease, The: Genetics And Biochemistry Of Atp Binding Cassette Transporters - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Abc Transporters Of Human Physiology And Disease, The: Genetics And Biochemistry Of Atp Binding Cassette Transporters write by Kenneth J Linton. This book was released on 2011-09-19. Abc Transporters Of Human Physiology And Disease, The: Genetics And Biochemistry Of Atp Binding Cassette Transporters available in PDF, EPUB and Kindle. ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins present in all cells of all species of archaea, eubacteria and eukaryota. The vast majority of these proteins control the transport across cellular membranes of molecules ranging from small ions to drugs, lipids and proteins. The human genome encodes 48 ABC transporter genes and mutations in most have been linked to disease. This book — that brings together state-of-the-art knowledge on ABC proteins in one volume — will provide students, professors and medical professionals with a background to the human ABC transporters that are known to be relevant to disease. Each of the 14 chapters is written by a leading researcher in the field. The genetics, structure and function of the proteins, and the future direction of research including the implications for human health are discussed in depth.
