Activation of Viruses by Host Proteases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Activation of Viruses by Host Proteases write by Eva Böttcher-Friebertshäuser. This book was released on 2018-05-22. Activation of Viruses by Host Proteases available in PDF, EPUB and Kindle. This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.
Viral Proteases and Their Inhibitors
Viral Proteases and Their Inhibitors - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Viral Proteases and Their Inhibitors write by Satya Prakash Gupta. This book was released on 2017-07-03. Viral Proteases and Their Inhibitors available in PDF, EPUB and Kindle. Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents. Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of each viral protease Presents an in-depth view of the structure and function of viral proteases
Textbook of Influenza
Textbook of Influenza - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Textbook of Influenza write by Robert G. Webster. This book was released on 2014-01-06. Textbook of Influenza available in PDF, EPUB and Kindle. The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health. Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain. This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering: • Influenza Perspectives • Structure and Replication • Evolution and Ecology • Epidemiology and Surveillance • Immunology • Vaccines and Vaccine Development • Clinical Aspects and Antivirals • Public Health Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.
Viral Proteases and Antiviral Protease Inhibitor Therapy
Viral Proteases and Antiviral Protease Inhibitor Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Viral Proteases and Antiviral Protease Inhibitor Therapy write by Uwe Lendeckel. This book was released on 2009-06-19. Viral Proteases and Antiviral Protease Inhibitor Therapy available in PDF, EPUB and Kindle. The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most important pathogenic viruses, responsible for severe diseases: AIDS, SARS, Hepatitis, Cytomegalovirus, T-cell lymphotropic virus, Picornavirus. This book focuses specifically on the viral proteases, crucial prerequisites for viral entry into cells and viral replication. Viral proteases represent an important pharmaceutical target. The current stage of protease inhibitor development and therapy are summarised and discussed by experts in the field. This volume represents a timely and valuable continuation of the Proteases in Biology and Disease series. The reader will learn the potential for proteases as targets for effective anti-virals. This book will be a valuable source of information on viral proteases and provoke further research in this important field.
Handbook of Antimicrobial Resistance
Handbook of Antimicrobial Resistance - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Handbook of Antimicrobial Resistance write by Matthias Gotte. This book was released on 2018-02-12. Handbook of Antimicrobial Resistance available in PDF, EPUB and Kindle. While many volumes have been written about various aspects of antimicrobial resistance, this book is a comprehensive reference work. All manifestations of resistance are addressed: viral; bacterial, parasitical and fungal are given dedicated sections. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target), are highly diverse. This work discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.
