Caffeine for the Sustainment of Mental Task Performance - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Caffeine for the Sustainment of Mental Task Performance write by Institute of Medicine. This book was released on 2002-01-07. Caffeine for the Sustainment of Mental Task Performance available in PDF, EPUB and Kindle. This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Adenosine Receptors in Neurodegenerative Diseases
Adenosine Receptors in Neurodegenerative Diseases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Adenosine Receptors in Neurodegenerative Diseases write by David Blum. This book was released on 2017-03-30. Adenosine Receptors in Neurodegenerative Diseases available in PDF, EPUB and Kindle. Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.
A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics
A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics write by Pier Andrea Borea. This book was released on 2009-12-01. A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics available in PDF, EPUB and Kindle. This book, with its 16 chapters, documents the present state of knowledge of the adenosine A receptor. It covers a wide range of information, including data from 3 studies of theoretical, molecular and cellular pharmacology, signal transduction, integrative physiology, new drug discoveries and clinical applications. It fills an important gap in the literature since no alternative source of such information is currently available. Although the A receptor is increasingly being recognized for 3 its increasing number of biological roles throughout the body and many A receptor 3 ligands have proven useful in elucidating peripheral and central pathologies, many issues remain unresolved. Moreover, research activity in this field continues to grow exponentially, resulting in a constant flow of new information. The chapters in this book cover both basic science and the relevant applications and provide an authoritative account of the current status of the field. They have enabled my goal as editor to make “A Adenosine Receptors from Cell Biology to Pharmacology and 3 Therapeutics” an up to date, scientifically excellent, reference source, attractive to basic and clinical scientists alike, a reality. Detailed understanding of the physico-chemical aspects and molecular biology of the A receptor provides a solid basis for its future development as a target for 3 adenosine-based pharmacotherapies (Chapters 2 and 3).
Adenosine Receptors and Parkinson's Disease
Adenosine Receptors and Parkinson's Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Adenosine Receptors and Parkinson's Disease write by Hiroshi Kase. This book was released on 1999-10-15. Adenosine Receptors and Parkinson's Disease available in PDF, EPUB and Kindle. This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function Proposes a hypothesis of adenosine A2A receptor function in the striatum Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints
Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing write by Charles E. Samuel. This book was released on 2011-11-06. Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing available in PDF, EPUB and Kindle. “The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins.”
