Adenosine Receptors in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Adenosine Receptors in Health and Disease write by Constance N. Wilson. This book was released on 2009-07-28. Adenosine Receptors in Health and Disease available in PDF, EPUB and Kindle. Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.
The Adenosine Receptors
The Adenosine Receptors - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Adenosine Receptors write by Pier Andrea Borea. This book was released on 2018-07-28. The Adenosine Receptors available in PDF, EPUB and Kindle. This book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and neurological diseases such as Huntington’s disease, Epilepsy, Parkinson’s disease and Alzheimer’s disease.
Imaging of the Human Brain in Health and Disease
Imaging of the Human Brain in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Imaging of the Human Brain in Health and Disease write by Philip Seeman. This book was released on 2013-11-15. Imaging of the Human Brain in Health and Disease available in PDF, EPUB and Kindle. Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. - A focused introduction to imaging healthy and diseased brains - Focuses on the primary neurotransmitter release - Includes sigma, acetylcholine, opioid, and dopamine receptors - Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease
Pharmacology of Purine and Pyrimidine Receptors
Pharmacology of Purine and Pyrimidine Receptors - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pharmacology of Purine and Pyrimidine Receptors write by . This book was released on 2011-07-13. Pharmacology of Purine and Pyrimidine Receptors available in PDF, EPUB and Kindle. This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. - Authors are the leading authorities in their fields - Subject matter is important for understanding tissue protection - Subject matter is of intense interest for new drug development
Caffeine for the Sustainment of Mental Task Performance
Caffeine for the Sustainment of Mental Task Performance - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Caffeine for the Sustainment of Mental Task Performance write by Institute of Medicine. This book was released on 2002-01-07. Caffeine for the Sustainment of Mental Task Performance available in PDF, EPUB and Kindle. This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
