Algorithms for Sample Preparation with Microfluidic Lab-on-Chip

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Release : 2022-09-01
Genre : Technology & Engineering
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Book Rating : 780/5 ( reviews)

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Algorithms for Sample Preparation with Microfluidic Lab-on-Chip write by Sukanta Bhattacharjee. This book was released on 2022-09-01. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip available in PDF, EPUB and Kindle. Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip

Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip

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Release : 2022-07-27
Genre : Technology & Engineering
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Book Rating : 732/5 ( reviews)

Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip write by Sudip Poddar. This book was released on 2022-07-27. Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip available in PDF, EPUB and Kindle. Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip

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Release : 2019-02-05
Genre : Technology & Engineering
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Book Rating : 557/5 ( reviews)

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Algorithms for Sample Preparation with Microfluidic Lab-on-Chip write by Bhattacharjee, Sukanta. This book was released on 2019-02-05. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip available in PDF, EPUB and Kindle. Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip

WALCOM: Algorithms and Computation

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Release : 2020-01-27
Genre : Computers
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Book Rating : 811/5 ( reviews)

WALCOM: Algorithms and Computation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook WALCOM: Algorithms and Computation write by M. Sohel Rahman. This book was released on 2020-01-27. WALCOM: Algorithms and Computation available in PDF, EPUB and Kindle. This book constitutes the refereed proceedings of the 14th International Conference on Algorithms and Computation, WALCOM 2020, held in Singapore in March/April 2020. The 23 full and 4 short papers presented were carefully reviewed and selected from 66 submissions. The papers focus on algorithmic graph theory and combinatorics, computational biology, computational geometry, data structures, experimental algorithm methodologies, graph algorithms, graph drawing, parallel and distributed algorithms, network optimization.

Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery

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Release : 2005-11-01
Genre : Science
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Book Rating : 725/5 ( reviews)

Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery write by Paul C.H. Li. This book was released on 2005-11-01. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery available in PDF, EPUB and Kindle. The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery focuses on all aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology, its limitations, and its breakthroughs over the years. It emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays and enzymatic assays. Originally conceived as a single chapter published in Ewing's Analytical Instrumentation, this book is a gateway to the vast literature and conference proceedings on the topic. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery expands upon its roots to present a comprehensive treatment of microfluidic lab-on-a-chip methods and applications for novices and advanced researchers alike.