An Introduction to Genetic Epidemiology

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Release : 2011-05-31
Genre : Medical
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Book Rating : 975/5 ( reviews)

An Introduction to Genetic Epidemiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook An Introduction to Genetic Epidemiology write by Palmer, Lyle J.. This book was released on 2011-05-31. An Introduction to Genetic Epidemiology available in PDF, EPUB and Kindle. This book brings together leading experts to provide an introduction to genetic epidemiology that begins with a primer in human molecular genetics through all the standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field.

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Book Rating : 983/5 ( reviews)

- read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook write by . This book was released on . available in PDF, EPUB and Kindle.

Fundamentals of Genetic Epidemiology

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Release : 1993
Genre : Medical
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Book Rating : 889/5 ( reviews)

Fundamentals of Genetic Epidemiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Fundamentals of Genetic Epidemiology write by Muin J. Khoury. This book was released on 1993. Fundamentals of Genetic Epidemiology available in PDF, EPUB and Kindle. This text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease aetiology. The authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations.

Genetic Epidemiology

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Release : 2013
Genre : Medical
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Book Rating : 818/5 ( reviews)

Genetic Epidemiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Genetic Epidemiology write by Melissa A. Austin. This book was released on 2013. Genetic Epidemiology available in PDF, EPUB and Kindle. Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described.

Genetic Epidemiology

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Release : 2018-06-07
Genre : Medical
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Book Rating : 670/5 ( reviews)

Genetic Epidemiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Genetic Epidemiology write by Evangelos Evangelou. This book was released on 2018-06-07. Genetic Epidemiology available in PDF, EPUB and Kindle. This volume details fast-moving research while providing in-depth descriptions of methods and analytical approaches that are helping to understand the genome and how it is related to complex diseases. Chapters guide the reader through common and rare variation, gene-gene and gene-environment interactions and state-of-the-art approaches for the synthesis of genome-wide and gene expression data. Novel approaches for associations in the HLA region, family-based designs, Mendelian Randomization and Copy Number Variation are also presented. The volume concludes with the challenges researchers face while moving from identifying variants to their functional role and potential drug targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, a thorough presentation of methods and approaches and tips on troubleshooting and avoiding known pitfalls.