Animal Models in Cancer Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Animal Models in Cancer Drug Discovery write by Asfar Azmi. This book was released on 2019-04-17. Animal Models in Cancer Drug Discovery available in PDF, EPUB and Kindle. Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.
Animal Models in Cancer Drug Discovery
Animal Models in Cancer Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Animal Models in Cancer Drug Discovery write by Asfar Azmi. This book was released on 2019-04-16. Animal Models in Cancer Drug Discovery available in PDF, EPUB and Kindle. Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field. - Encompasses discussions on innovative animal models, xenograft, genetic models, primary models, organoid systems, humanized and other models in modern biology paradigms that are enhancing research in the field of drug discover - Covers the use of these models in personalized medicine, immunotherapy, toxicology, pre-IND assessments and related drug development arenas - Presents protocols, procedures, and a comprehensive glossary to help new readers understand technical terms and specialized nomenclature
Tumor Models in Cancer Research
Tumor Models in Cancer Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Tumor Models in Cancer Research write by Beverly A. Teicher. This book was released on 2001-11-07. Tumor Models in Cancer Research available in PDF, EPUB and Kindle. Beverly A. Teicher and a panel of leading experts comprehensively describe for the first time in many years the state-of-the-art in animal tumor model research. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, transgenic models, and gene knockout models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.
Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach
Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach write by Kakoli Bose. This book was released on 2019-11-25. Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach available in PDF, EPUB and Kindle. Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
Alternatives to Animal Testing
Alternatives to Animal Testing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Alternatives to Animal Testing write by Hajime Kojima. This book was released on 2018-12-27. Alternatives to Animal Testing available in PDF, EPUB and Kindle. This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
