Animal Models of Human Birth Defects - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Animal Models of Human Birth Defects write by Aimin Liu. This book was released on 2020-04-17. Animal Models of Human Birth Defects available in PDF, EPUB and Kindle. This book focuses on the use of animal models to study various human defects. It summarizes our current understanding of a variety of common human birth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms leading to many of these developmental disorders has hindered effective prevention and early intervention strategies. Studies using animal models have provided essential insights into several human birth defects. This book serves as a valuable reference resource for researchers and graduate students who are interested in learning the basic principles as well as the latest advances in the study of the mechanisms of human birth defects.
Animal Models of Human Birth Defects
Animal Models of Human Birth Defects - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Animal Models of Human Birth Defects write by Aimin Liu. This book was released on 2020. Animal Models of Human Birth Defects available in PDF, EPUB and Kindle. This book focuses on the use of animal models to study various human defects. It summarizes our current understanding of a variety of common human birth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms leading to many of these developmental disorders has hindered effective prevention and early intervention strategies. Studies using animal models have provided essential insights into several human birth defects. This book serves as a valuable reference resource for researchers and graduate students who are interested in learning the basic principles as well as the latest advances in the study of the mechanisms of human birth defects.
Mouse Models of Developmental Genetic Disease
Mouse Models of Developmental Genetic Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mouse Models of Developmental Genetic Disease write by . This book was released on 2011-09-06. Mouse Models of Developmental Genetic Disease available in PDF, EPUB and Kindle. Approximately three percent of newborn humans have congenital anomalies with significant cosmetic and/or functional consequences. Much of our ability to understand what has gone awry in these birth defects rests with development of animal models for them; the mouse has emerged as the model organism of choice for these studies. This volume reviews mouse models of specific developmental genetic diseases, including neural tube defects; cleft lip and/or palate; congenital heart disease; ciliopathies; hereditary deafness and others to provide conceptual insight into congenital anomalies generally. The interplay between clinical observation and murine model systems is expected to yield deep insight into mammalian developmental processes and the emergence of effective preventive and/or therapeutic strategies. Provides busy clinical and basic science researchers a one-stop overview and synthesis of the latest research findings and contemporary thought in the area Allows researchers to compare and contrast disease models and also to learn about what models have been developed for large-scale distribution Allows researchers to evaluate basic differences in mouse and human biology and propose alternate pathways and possible gene interactions of the disease
Scientific Frontiers in Developmental Toxicology and Risk Assessment
Scientific Frontiers in Developmental Toxicology and Risk Assessment - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Scientific Frontiers in Developmental Toxicology and Risk Assessment write by National Research Council. This book was released on 2000-12-21. Scientific Frontiers in Developmental Toxicology and Risk Assessment available in PDF, EPUB and Kindle. Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Human Risk Assessment
Human Risk Assessment - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Human Risk Assessment write by M V Roloff. This book was released on 2020-10-28. Human Risk Assessment available in PDF, EPUB and Kindle. This book explores the factors which are critical in the selection of an appropriate animal species for toxicology studies and the subsequent extrapolation of the data to humans. It provides some future directions for risk assessment activities at the Environmental Protection Agency.
