Antibiotic Discovery and Development - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antibiotic Discovery and Development write by Thomas J. Dougherty. This book was released on 2011-12-18. Antibiotic Discovery and Development available in PDF, EPUB and Kindle. This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Antibacterial Drug Discovery to Combat MDR
Antibacterial Drug Discovery to Combat MDR - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antibacterial Drug Discovery to Combat MDR write by Iqbal Ahmad. This book was released on 2019-11-09. Antibacterial Drug Discovery to Combat MDR available in PDF, EPUB and Kindle. This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.
Antibiotic Drug Discovery
Antibiotic Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antibiotic Drug Discovery write by Steven M Firestine. This book was released on 2017-05-19. Antibiotic Drug Discovery available in PDF, EPUB and Kindle. Recent years have seen a resurgence of antibiotic drug discovery. This book brings together the relevant information to assess the state-of-the-art. It identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities. Addressing the need for continued investment in antibiotic drug development, the book provides a point of reference for the rapidly expanding infectious disease research community. In addition to its attention on new targets, the book focusses on the medicinal chemistry and chemistry of the targets. Within this framework, chapters from leading researchers in academia and industry address findings in important areas such as biofilm production, narrow spectrum antibiotics and novel antibacterials from previously uncultured soil bacteria. This book will be a useful resource for postgraduate students and researchers in medicinal chemistry wishing to understand the latest approaches to antibiotic drug discovery.
Challenges to Tackling Antimicrobial Resistance
Challenges to Tackling Antimicrobial Resistance - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Challenges to Tackling Antimicrobial Resistance write by Michael Anderson. This book was released on 2020-04-23. Challenges to Tackling Antimicrobial Resistance available in PDF, EPUB and Kindle. An accessible overview of the challenges in tackling AMR, and the economic and policy responses of the 'One Health' approach. It will appeal to policy-makers seeking to strengthen national and local polices tackling AMR, as well as students and academics who want an overview of the latest scientific evidence regarding effective AMR policies.
Drug Discovery Targeting Drug-Resistant Bacteria
Drug Discovery Targeting Drug-Resistant Bacteria - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drug Discovery Targeting Drug-Resistant Bacteria write by Prashant Kesharwani. This book was released on 2020-05-29. Drug Discovery Targeting Drug-Resistant Bacteria available in PDF, EPUB and Kindle. Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war
