Antisense Research and Application - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antisense Research and Application write by Stanley T. Crooke. This book was released on 2012-12-06. Antisense Research and Application available in PDF, EPUB and Kindle. Antisense technology may result in dramatic changes in the therapy of many diseases and may provide tools to dissect pharmacological processes and to confirm the roles of various genes. In this volume, progress in the understanding of antisense technology and its use in creating new drugs is discussed. Potential caveats, pitfalls and limitations of the technology are also presented. In the next few years the pace at which new molecular targets will be identified will increase exponentially as the sequencing of the human genome and of other genomes proceeds.
Antisense Research and Applications
Antisense Research and Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antisense Research and Applications write by Stanley T. Crooke. This book was released on 1993-05-27. Antisense Research and Applications available in PDF, EPUB and Kindle. Antisense Research and Applications is a comprehensive review of oligonucleotide research covering molecular biological advances in this field, the current status of antisense drug research, and strategies for future research and therapeutic applications. In bringing together the latest research from an array of authoritative scientists, Antisense Research and Applications provides an integrated conceptual basis for considering oligonucleotide therapeutics. Topics covered in the 32 chapters of this book include nucleic acid structure and function, antisense RNA, medicinal chemistry of oligonucleotides, analogs, pharmacokinetics and toxicology, and activities of current antisense drugs. This volume addresses advances in a broad range of disciplines and is an excellent resource for basic researchers and applied investigators in pharmaceutical laboratories and in such fields as biochemistry and molecular biology.
Antisense Drug Technology
Antisense Drug Technology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antisense Drug Technology write by Stanley T. Crooke. This book was released on 2007-07-25. Antisense Drug Technology available in PDF, EPUB and Kindle. Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generati
Applied Antisense Oligonucleotide Technology
Applied Antisense Oligonucleotide Technology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Applied Antisense Oligonucleotide Technology write by Cy A. Stein. This book was released on 1998-03-19. Applied Antisense Oligonucleotide Technology available in PDF, EPUB and Kindle. Applied Antisense Oligonucleotide Technology provides the basic concepts as well as the practical concerns associated with the use of antisense oligonucleotides to modify gene expression. Chapters include oligonucleotide chemistry, DNA triplex formation, delivery mechanisms, pharmocokinetics, toxicity, oligonucleotides.
Manual of Antisense Methodology
Manual of Antisense Methodology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Manual of Antisense Methodology write by Gunther Hartmann. This book was released on 2012-12-06. Manual of Antisense Methodology available in PDF, EPUB and Kindle. In the past few years, antisense methodology has moved from in vitro studies to in vivo studies and first human trials. While the basic concept of antisense technology is simple, the methodological problems associated with its use are numerous and complex. Antisense- based methods have proven to be a field of research where careful attention to experimental protocols and appropriate controls is necessary. The Manual of Antisense Methodology emphasizes the application of antisense oligonucleotides, and is a guide for the identification of antisense and non-antisense effects in different experimental settings. The work is organized into three sections: antisense application in vitro, antisense application in vivo (animal models) and finally, clinical antisense studies. Where at all possible, the methods are described in sufficient detail to allow reproduction of a given experiment. The Manual of Antisense Methodology will be of interest to researchers in immunology, cancer research, pharmacology and internal medicine; and physicians conducting clinical studies in these fields.
