Artemisinin-Based and Other Antimalarials - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Artemisinin-Based and Other Antimalarials write by Guoqiao Li. This book was released on 2017-11-28. Artemisinin-Based and Other Antimalarials available in PDF, EPUB and Kindle. Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery
Saving Lives, Buying Time
Saving Lives, Buying Time - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Saving Lives, Buying Time write by Institute of Medicine. This book was released on 2004-09-09. Saving Lives, Buying Time available in PDF, EPUB and Kindle. For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.
Economic Analysis of Malaria Control in Sub-Saharan Africa
Economic Analysis of Malaria Control in Sub-Saharan Africa - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Economic Analysis of Malaria Control in Sub-Saharan Africa write by Catherine Cavallaro Goodman. This book was released on 2000. Economic Analysis of Malaria Control in Sub-Saharan Africa available in PDF, EPUB and Kindle.
Hepatotoxicity
Hepatotoxicity - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hepatotoxicity write by Hyman J. Zimmerman. This book was released on 1999. Hepatotoxicity available in PDF, EPUB and Kindle. Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Antimalarial Chemotherapy
Antimalarial Chemotherapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antimalarial Chemotherapy write by Philip J. Rosenthal. This book was released on 2001-04-01. Antimalarial Chemotherapy available in PDF, EPUB and Kindle. Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.
