Assessing Ocular Toxicology in Laboratory Animals

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Release : 2012-12-04
Genre : Medical
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Book Rating : 642/5 ( reviews)

Assessing Ocular Toxicology in Laboratory Animals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Assessing Ocular Toxicology in Laboratory Animals write by Andrea B Weir. This book was released on 2012-12-04. Assessing Ocular Toxicology in Laboratory Animals available in PDF, EPUB and Kindle. Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.

Assessing Ocular Toxicology in Laboratory Animals

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Release : 2012-12-01
Genre :
Kind :
Book Rating : 653/5 ( reviews)

Assessing Ocular Toxicology in Laboratory Animals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Assessing Ocular Toxicology in Laboratory Animals write by Springer. This book was released on 2012-12-01. Assessing Ocular Toxicology in Laboratory Animals available in PDF, EPUB and Kindle.

Guide for the Care and Use of Laboratory Animals

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Release : 2011-01-27
Genre : Science
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Book Rating : 006/5 ( reviews)

Guide for the Care and Use of Laboratory Animals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Guide for the Care and Use of Laboratory Animals write by National Research Council. This book was released on 2011-01-27. Guide for the Care and Use of Laboratory Animals available in PDF, EPUB and Kindle. A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Standards for Ocular Toxicology and Inflammation

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Release : 2018-09-18
Genre : Medical
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Book Rating : 635/5 ( reviews)

Standards for Ocular Toxicology and Inflammation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Standards for Ocular Toxicology and Inflammation write by Brian C. Gilger. This book was released on 2018-09-18. Standards for Ocular Toxicology and Inflammation available in PDF, EPUB and Kindle. This book is an international effort to standardize the language, terms, and methods used in ocular toxicology.With over 300 color illustrations this consensus volume provides standards and harmonization for procedures, terminology, and scoring schemes for ocular toxicology. it is essential for industry, pharmaceutical companies, and governmental agencies to help improve the drug development process and to reduce and refine the use of animals in research. Standards for Ocular Toxicology and Inflammation is endorsed by the American College of Veterinary Ophthalmologists.

Atlas of Toxicological Pathology

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Release : 2014-05-13
Genre : Medical
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Book Rating : 988/5 ( reviews)

Atlas of Toxicological Pathology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Atlas of Toxicological Pathology write by Chirukandath Gopinath. This book was released on 2014-05-13. Atlas of Toxicological Pathology available in PDF, EPUB and Kindle. This atlas contains more than 700 illustrations that the authors have collected over the years as well as references and information pertaining to recently developed drug classes, including biologics. It is a useful bench reference for practicing pathologists and may also be used as a reference text by other experts from related fields. The atlas is organised into different chapters based on systemic pathology. Each chapter has illustrations with legends, and the atlas includes some rare examples of unique lesions found during toxicity studies over many years.