Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

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Release : 2016-12-28
Genre : Medical
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Book Rating : 273/5 ( reviews)

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging write by M. A. Hayat. This book was released on 2016-12-28. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging available in PDF, EPUB and Kindle. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. Presents the most advanced information regarding the role of the autophagic system in life and death Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Includes chapters authored by leaders in the field around the globeā€”the broadest, most expert coverage available

Autophagy in Health and Disease

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Author :
Release : 2021-09-22
Genre : Science
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Book Rating : 04X/5 ( reviews)

Autophagy in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Autophagy in Health and Disease write by Beverly Rothermel. This book was released on 2021-09-22. Autophagy in Health and Disease available in PDF, EPUB and Kindle. Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory of the research field, mechanisms of autophagy, and autophagy regulation. The second section (Chapters 8-11) details developmental aspects, including stem cells, embryogenesis, hematopoiesis, and paligenosis. The subsequent sections are devoted to the role of autophagy in specific organ systems involved in metabolic control and diabetes (Chapters 12-15), the cardiovascular system (Chapters 16-18), and the nervous system (Chapters 19-20). The final section (Chapters 21-28) addresses autophagy in other organ systems vital to human health and longevity. Also included are chapters on microautophagy, chaperone-mediated autophagy, and the potential for autophagy as a therapeutic target. Autophagy in Health and Disease is invaluable to anyone new to the field as well as established investigators looking for a broader understanding of autophagy from outside their specific field of study. Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathology Offers extended coverage of the mechanisms that mediate autophagy Covers the role of autophagy in stem cells and induced pluripotent stem cells, as well as the regenerative process of paligenosis Highlights important questions that remain to be addressed

Autophagy in Health and Disease

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Release : 2018-10-06
Genre : Science
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Book Rating : 463/5 ( reviews)

Autophagy in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Autophagy in Health and Disease write by Kursad Turksen. This book was released on 2018-10-06. Autophagy in Health and Disease available in PDF, EPUB and Kindle. This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students.

Exercise, Autophagy and Chronic Diseases

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Release : 2021-09-30
Genre : Medical
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Book Rating : 256/5 ( reviews)

Exercise, Autophagy and Chronic Diseases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Exercise, Autophagy and Chronic Diseases write by Ning Chen. This book was released on 2021-09-30. Exercise, Autophagy and Chronic Diseases available in PDF, EPUB and Kindle. This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

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Release : 2017-02-20
Genre :
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Book Rating : 208/5 ( reviews)

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging write by M A Hayat. This book was released on 2017-02-20. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging available in PDF, EPUB and Kindle. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. This is the 11 volume of the multivolume series, Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. The series discusses in detail almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 11 of the Autophagy series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Presents the most advanced information regarding the role of the autophagic system in life and death and whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available