Principles of Translational Science in Medicine

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Release : 2015-04-02
Genre : Science
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Book Rating : 214/5 ( reviews)

Principles of Translational Science in Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Principles of Translational Science in Medicine write by Martin Wehling. This book was released on 2015-04-02. Principles of Translational Science in Medicine available in PDF, EPUB and Kindle. Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. - Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development - New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies - Details IPR issues of translation, especially for public-private-partnerships - Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Translational Biomedical Informatics

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Release : 2016-10-31
Genre : Science
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Book Rating : 031/5 ( reviews)

Translational Biomedical Informatics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Translational Biomedical Informatics write by Bairong Shen. This book was released on 2016-10-31. Translational Biomedical Informatics available in PDF, EPUB and Kindle. This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.

Translational Systems Biology: Concepts and Practice for the Future of Biomedical Research

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Release : 2017-11-13
Genre : Computers
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Book Rating : 476/5 ( reviews)

Translational Systems Biology: Concepts and Practice for the Future of Biomedical Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Translational Systems Biology: Concepts and Practice for the Future of Biomedical Research write by Yoram Vodovotz. This book was released on 2017-11-13. Translational Systems Biology: Concepts and Practice for the Future of Biomedical Research available in PDF, EPUB and Kindle. Are we satisfied with the rate of drug development? Are we happy with the drugs that come to market? Are we getting our money s worth in spending for basic biomedical research? In Translational Systems Biology, Drs. Yoram Vodovotz and Gary An address these questions by providing a foundational description the barriers facing biomedical research today and the immediate future, and how these barriers could be overcome through the adoption of a robust and scalable approach that will form the underpinning of biomedical research for the future. By using a combination of essays providing the intellectual basis of the Translational Dilemma and reports of examples in the study of inflammation, the content of Translational Systems Biology will remain relevant as technology and knowledge advances bring broad translational applicability to other diseases. Translational systems biology is an integrated, multi-scale, evidence-based approach that combines laboratory, clinical and computational methods with an explicit goal of developing effective means of control of biological processes for improving human health and rapid clinical application. This comprehensive approach to date has been utilized for in silico studies of sepsis, trauma, hemorrhage, and traumatic brain injury, acute liver failure, wound healing, and inflammation. Provides an explicit, reasoned, and systematic approach to dealing with the challenges of translational science across disciplines Establishes the case for including computational modeling at all stages of biomedical research and healthcare delivery, from early pre-clinical studies to long-term care, by clearly delineating efficiency and costs saving important to business investment Guides readers on how to communicate across domains and disciplines, particularly between biologists and computational researchers, to effectively develop multi- and trans-disciplinary research teams "

A Practical Guide to Biomedical Research

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Release : 2017-10-27
Genre : Medical
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Book Rating : 824/5 ( reviews)

A Practical Guide to Biomedical Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook A Practical Guide to Biomedical Research write by Peter Agger. This book was released on 2017-10-27. A Practical Guide to Biomedical Research available in PDF, EPUB and Kindle. This book advises and supports novice researchers in taking their first steps into the world of scientific research. Through practical tips and tricks presented in a clear, concise and step-wise manner, the book describes the entire research process from idea to publication. It also gives the reader insight into the vast opportunities a research career can provide. The books target demographic is aspiring researchers within the biomedical professions, be it medical students, young doctors, nurses, engineers, physiotherapists etc. The book will help aspirational inexperienced researchers turn their intentions into actions, providing crucial guidance for successful entry into the field of biomedical research.

From Auto- to Allotransplantation

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Release : 2016-06-28
Genre : Medical
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Book Rating : 67X/5 ( reviews)

From Auto- to Allotransplantation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook From Auto- to Allotransplantation write by F.-C. Wei. This book was released on 2016-06-28. From Auto- to Allotransplantation available in PDF, EPUB and Kindle. This unique publication was written by experts who have made significant contributions to the development of reconstructive microsurgery and vascularized composite allotransplantation and are likely to shape its future. The book is divided into three major sections. The first presents the state-of-the-art of autologous microsurgical reconstruction. It summarizes current achievements, highlights the shortcomings of currently available techniques, and prepares the reader for the next evolutionary step: allotransplantation. Section two is a comprehensive review of allotransplantation, from immunology to surgical techniques. Finally, for those interested in establishing a comprehensive center for vascularized composite allotransplantation, section three provides important lessons from the successful Chang Gung Vascularized Composite Allotransplantation Center. From Auto- to Allotransplantation is indeed the only up-to-date and complete reference available on the topic. Scholars and research fellows interested in transplantation will benefit greatly from this work. It is also an invaluable resource for plastic, orthopedic, hand, ENT, oromaxillofacial, and general surgeons as well as for residents.