Cancer Systems Biology, Bioinformatics and Medicine

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Release : 2011-08-21
Genre : Medical
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Book Rating : 676/5 ( reviews)

Cancer Systems Biology, Bioinformatics and Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cancer Systems Biology, Bioinformatics and Medicine write by Alfredo Cesario. This book was released on 2011-08-21. Cancer Systems Biology, Bioinformatics and Medicine available in PDF, EPUB and Kindle. This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.

Cancer Systems Biology, Bioinformatics and Medicine

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Release : 2011-08-25
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Book Rating : 684/5 ( reviews)

Cancer Systems Biology, Bioinformatics and Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cancer Systems Biology, Bioinformatics and Medicine write by . This book was released on 2011-08-25. Cancer Systems Biology, Bioinformatics and Medicine available in PDF, EPUB and Kindle.

Systems Biology in Cancer Research and Drug Discovery

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Release : 2012-09-29
Genre : Medical
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Book Rating : 191/5 ( reviews)

Systems Biology in Cancer Research and Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Systems Biology in Cancer Research and Drug Discovery write by Asfar S Azmi. This book was released on 2012-09-29. Systems Biology in Cancer Research and Drug Discovery available in PDF, EPUB and Kindle. Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and in clinical trial design. This book reviews the state-of-the-art knowledge and touches upon cutting edge newer and improved applications especially in the area of network modeling. It is aimed at an audience ranging from students, academics, basic researcher and clinicians in cancer research. This book is expected to benefit the field of translational cancer medicine by bridging the gap between basic researchers, computational biologists and clinicians who have one ultimate goal and that is to defeat cancer.

Cancer Systems Biology

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Release : 2019-06-04
Genre : Medical
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Book Rating : 036/5 ( reviews)

Cancer Systems Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cancer Systems Biology write by Louise von Stechow. This book was released on 2019-06-04. Cancer Systems Biology available in PDF, EPUB and Kindle. This book comprises protocols describing systems biology methodologies and computational tools, offering a variety of ways to analyze different types of high-throughput cancer data. Chapters give an overview over data types available in large-scale data repositories and state-of-the-art methods used in the field of cancer systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Systems Biology : Methods and Protocols aims to ensure successful results in the further study of this vital field. The chapters "Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels", "Perseus: A Bioinformatics Platform for Integrative Analysis of Proteomics Data in Cancer Research" and "Phosphoproteomics-based Profiling of Kinase Activities in Cancer Cells" are available open access under a CC BY 4.0 license via link.springer.com.

Computational Systems Biology Approaches in Cancer Research

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Release : 2019-09-09
Genre : Computers
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Book Rating : 927/5 ( reviews)

Computational Systems Biology Approaches in Cancer Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Computational Systems Biology Approaches in Cancer Research write by Inna Kuperstein. This book was released on 2019-09-09. Computational Systems Biology Approaches in Cancer Research available in PDF, EPUB and Kindle. Praise for Computational Systems BiologyApproaches in Cancer Research: "Complex concepts are written clearly and with informative illustrations and useful links. The book is enjoyable to read yet provides sufficient depth to serve as a valuable resource for both students and faculty." — Trey Ideker, Professor of Medicine, UC Xan Diego, School of Medicine "This volume is attractive because it addresses important and timely topics for research and teaching on computational methods in cancer research. It covers a broad variety of approaches, exposes recent innovations in computational methods, and provides acces to source code and to dedicated interactive web sites." — Yves Moreau, Department of Electrical Engineering, SysBioSys Centre for Computational Systems Biology, University of Leuven With the availability of massive amounts of data in biology, the need for advanced computational tools and techniques is becoming increasingly important and key in understanding biology in disease and healthy states. This book focuses on computational systems biology approaches, with a particular lens on tackling one of the most challenging diseases - cancer. The book provides an important reference and teaching material in the field of computational biology in general and cancer systems biology in particular. The book presents a list of modern approaches in systems biology with application to cancer research and beyond. It is structured in a didactic form such that the idea of each approach can easily be grasped from the short text and self-explanatory figures. The coverage of topics is diverse: from pathway resources, through methods for data analysis and single data analysis to drug response predictors, classifiers and image analysis using machine learning and artificial intelligence approaches. Features Up to date using a wide range of approaches Applicationexample in each chapter Online resources with useful applications’