Cartilage Repair Strategies

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Release : 2008-01-23
Genre : Medical
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Book Rating : 439/5 ( reviews)

Cartilage Repair Strategies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cartilage Repair Strategies write by Riley J. Williams. This book was released on 2008-01-23. Cartilage Repair Strategies available in PDF, EPUB and Kindle. The focus of this book is to create a comprehensive analysis of cartilage injury and repair strategies. Twenty chapters cover proven and emerging procedures and methodologies. Readers will be able to understand the clinical problem, appropriate diagnosis, and repair strategies relevant to first line and secondary cartilage repair procedures.

Cartilage and Osteoarthritis

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Release : 2008-02-01
Genre : Medical
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Book Rating : 102/5 ( reviews)

Cartilage and Osteoarthritis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cartilage and Osteoarthritis write by Massimo Sabatini. This book was released on 2008-02-01. Cartilage and Osteoarthritis available in PDF, EPUB and Kindle. Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover.

Cartilage Injury of the Knee

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Release : 2021-08-31
Genre : Medical
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Book Rating : 511/5 ( reviews)

Cartilage Injury of the Knee - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cartilage Injury of the Knee write by Aaron J. Krych. This book was released on 2021-08-31. Cartilage Injury of the Knee available in PDF, EPUB and Kindle. Cartilage injuries of the knee are common, and diagnosis and treatment options have continued to evolve. This book focuses on current non-operative and surgical treatment strategies for articular cartilage injuries, highlighting the controversies and different approaches from an international perspective. This book includes information on the basic science of cartilage structure and function, expert perspectives on imaging and diagnosing, as well as work-up of athletes and patients presenting with acute or chronic cartilage injury. It also provides an evidence base for current cutting-edge cartilage repair and restoration. Written by leading experts in the field, the book, published in collaboration with ISAKOS and ICRS, is vital reading for orthopaedic and sports medicine surgeons, fellows and residents. It is also of interest to sports trainers, physiotherapists, medical students, postgraduate students, and physical medicine and rehabilitation specialists.

Articular Cartilage Tissue Engineering

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Release : 2010
Genre : Medical
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Book Rating : 755/5 ( reviews)

Articular Cartilage Tissue Engineering - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Articular Cartilage Tissue Engineering write by Kyriacos A. Athanasiou. This book was released on 2010. Articular Cartilage Tissue Engineering available in PDF, EPUB and Kindle. Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions

Mesenchymal Stem Cell Derived Exosomes

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Release : 2015-09-02
Genre : Science
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Book Rating : 975/5 ( reviews)

Mesenchymal Stem Cell Derived Exosomes - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mesenchymal Stem Cell Derived Exosomes write by Yaoliang Tang. This book was released on 2015-09-02. Mesenchymal Stem Cell Derived Exosomes available in PDF, EPUB and Kindle. Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. - Introduces the MSC-exosome mediated cell-cell communication - Covers the major functional benefits in current MSC-derived exosome studies - Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies