Cell Biology of Extracellular Matrix - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell Biology of Extracellular Matrix write by E.D. Hay. This book was released on 2013-11-11. Cell Biology of Extracellular Matrix available in PDF, EPUB and Kindle. In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
The Extracellular Matrix: an Overview
The Extracellular Matrix: an Overview - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Extracellular Matrix: an Overview write by Robert Mecham. This book was released on 2011-02-16. The Extracellular Matrix: an Overview available in PDF, EPUB and Kindle. Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Cell Biology of Extracellular Matrix
Cell Biology of Extracellular Matrix - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell Biology of Extracellular Matrix write by Elizabeth D. Hay. This book was released on 2012-12-06. Cell Biology of Extracellular Matrix available in PDF, EPUB and Kindle. At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears. After all, the matrix is EXTRAcellular, outside the cells. In this book, however, the authors make a compelling case for the relevance of the matrix to cellular concerns. Not only are numerous cell types, including many epithelia, quite caught up in the business of manufacturing matrix components, but also most of them contain matrix molecules in exoskeletons that are attached to the plasmalemma and that organize or otherwise influence the affairs of the cyto plasm. The idea of this book is to present the extracellular matrix to cell biolo gists of all levels. The authors are active and busy investigators, recognized experts in their fields, but all were enthusiastic about the prospect of writing for this audience. The chapters are not "review" articles in the usual sense, nor are they rehashes of symposium talks; they were written specifically for this book and they present the "state of the art" in engaging style, with ample references to more technical or historical reviews. The book is rich in electron micro graphs and diagrams and for many of the latter, as well as for the design of the cover, we are indebted to Sylvia J. Keene, medical illustrator for the Department of Anatomy at Harvard Medical Scrool. We also owe special thanks to Susan G.
Molecular Biology of The Cell
Molecular Biology of The Cell - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of The Cell write by Bruce Alberts. This book was released on 2002. Molecular Biology of The Cell available in PDF, EPUB and Kindle.
Extracellular Matrix Assembly and Structure
Extracellular Matrix Assembly and Structure - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Extracellular Matrix Assembly and Structure write by Peter D. Yurchenco. This book was released on 2013-10-22. Extracellular Matrix Assembly and Structure available in PDF, EPUB and Kindle. The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix. Addresses assembly of most of the known classes of extracellular matrix macromolecules Discusses higher order structures produced by ECM Gives important concepts in ECM and cell-matrix interactions, Protein structure and protein-protein interactions, Development and tissue remodeling
