Cellular Therapies for Retinal Disease

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Release : 2017-06-20
Genre : Science
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Book Rating : 791/5 ( reviews)

Cellular Therapies for Retinal Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cellular Therapies for Retinal Disease write by Steven D. Schwartz. This book was released on 2017-06-20. Cellular Therapies for Retinal Disease available in PDF, EPUB and Kindle. This book familiarizes the reader with the current landscape of cell-based therapies for the treatment of retinal disease, including diseases that affect the choriocapillaris, retinal pigment epithelium, photoreceptors, and retinal ganglion cells. Instead of utilizing a disease-centric approach to the topic, this book—edited by two world-renowned stem cell scientists—focuses on strategies for developing and transplanting the cells. This includes the creation of replacement cells, cell-based neuroprotection, and in vitro disease modeling and testing. The final chapters briefly review parallel approaches that do not directly utilize cellular transplantation. The use of cellular transplantation to treat retinal disease has recently become a viable and exciting therapeutic approach. The visibility of the retina and its laminar cellular architecture render it an ideal organ for the development of surgically delivered cellular therapies. Having an in-depth understanding of the current state of cell therapy for the eye is an essential first step toward utilizing similar approaches in other organs. Ophthalmologists, translational clinician-scientists, stem cell scientists, and researchers interested in eye disease will find Cellular Therapies for Retinal Disease: A Strategic Approach essential reading and it is also suitable for workshops or courses at the undergraduate or Ph.D. level.

Cell-Based Therapy for Degenerative Retinal Disease

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Release : 2019-03-01
Genre : Science
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Book Rating : 222/5 ( reviews)

Cell-Based Therapy for Degenerative Retinal Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell-Based Therapy for Degenerative Retinal Disease write by Marco A. Zarbin. This book was released on 2019-03-01. Cell-Based Therapy for Degenerative Retinal Disease available in PDF, EPUB and Kindle. This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.

Cell-Based Therapy for Retinal Degenerative Disease

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Release : 2014-04-22
Genre : Science
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Book Rating : 852/5 ( reviews)

Cell-Based Therapy for Retinal Degenerative Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell-Based Therapy for Retinal Degenerative Disease write by R.P. Casaroli-Marano. This book was released on 2014-04-22. Cell-Based Therapy for Retinal Degenerative Disease available in PDF, EPUB and Kindle. In this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading.

Pluripotent Stem Cells in Eye Disease Therapy

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Release : 2019-10-25
Genre : Science
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Book Rating : 719/5 ( reviews)

Pluripotent Stem Cells in Eye Disease Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pluripotent Stem Cells in Eye Disease Therapy write by Kapil Bharti. This book was released on 2019-10-25. Pluripotent Stem Cells in Eye Disease Therapy available in PDF, EPUB and Kindle. This book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for degenerative eye diseases. Chapters are contributed by experts in the field and cover such topics as the use of pluripotent stem cells in 2D and 3D engineering of ocular tissues for disease modelling and drug testing as well as approaches to replace degenerated RPE and photoreceptors in macular degeneration and retinitis pigmentosa. Pluripotent Stem Cells in Eye Disease Therapy presents a comprehensive discussion of basic science and clinical applications and is an indispensable resource for everyone from advanced graduate students to advanced professionals who want to learn about the potential of stem cell biology and its role in the field of retinal diseases.

Ocular Neuroprotection

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Release : 2003-07-15
Genre : Medical
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Book Rating : 946/5 ( reviews)

Ocular Neuroprotection - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ocular Neuroprotection write by Leonard A. Levin. This book was released on 2003-07-15. Ocular Neuroprotection available in PDF, EPUB and Kindle. Many retinal and optic nerve disorders have no effective therapy, or are treated incompletely and with considerable side effects. Recent advances have suggested the significant benefits associated with neuroprotection - that is, when treatment strategies are directed to photoreceptors, retinal ganglion cells, or other neural targets. Enter Ocular N