Chemical Biology of Glycoproteins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Chemical Biology of Glycoproteins write by Zhongping Tan. This book was released on 2017-03-27. Chemical Biology of Glycoproteins available in PDF, EPUB and Kindle. Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions. Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.
Essentials of Glycobiology
Essentials of Glycobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Essentials of Glycobiology write by Ajit Varki. This book was released on 1999. Essentials of Glycobiology available in PDF, EPUB and Kindle. Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Addressing Roles for Glycans in Immunology using Chemical Biology
Addressing Roles for Glycans in Immunology using Chemical Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Addressing Roles for Glycans in Immunology using Chemical Biology write by Matthew S. Macauley. This book was released on 2020-07-17. Addressing Roles for Glycans in Immunology using Chemical Biology available in PDF, EPUB and Kindle.
Glycoscience
Glycoscience - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Glycoscience write by Bertram O. Fraser-Reid. This book was released on 2008-04-14. Glycoscience available in PDF, EPUB and Kindle. As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.
Glycobiology Protocols
Glycobiology Protocols - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Glycobiology Protocols write by Inka Brockhausen. This book was released on 2008-02-04. Glycobiology Protocols available in PDF, EPUB and Kindle. Glycobiology involves studies of complex carbohydrates and posttrans- tional modifications of proteins, and has become an important interdiscip- nary field encompassing chemistry, biochemistry, biology, physiology, and pathology. Although initial research was directed toward elucidation of the different carbohydrate structures and the enzymes synthesizing them, the field has now moved toward identifying the functions of carbohydrates. The pro- cols described in Glycobiology Protocols form a solid basis for investigations of glycan functions in health and disease. The cloning of many of the genes participating in glycosylation processes has helped to enhance our knowledge of how glycosylation is controlled, but has also added another dimension of complexity to the great heterogeneous variety of the structures of the oligos- charides of glycoproteins, proteoglycans, and glycolipids. A family of similar enzyme proteins exists for each glycosylation step. Glycosyltransferases are extremely specific for both the nucleotide sugar donor and the acceptor s- strate, but many other factors control sugar transfer, including the locali- tion and topology of enzymes, cofactors, possible chaperone proteins, and the availability of sugar acceptor substrates. The analysis of the intracellular organization of glycosylation and of the factors controlling the activities of the participating enzymes in the cell are important areas that need more research efforts. Another challenge for future research is to understand the glycodynamics of a cell, that is, how the cell responds to stimuli leading to biological and pathological changes in terms of alterations in glycosylation, and how this affects the biology of the cell.
