Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide

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Release : 2015-07-10
Genre : Medical
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Book Rating : 440/5 ( reviews)

Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide write by Philip K. Moore. This book was released on 2015-07-10. Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide available in PDF, EPUB and Kindle. This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.

Redox Biochemistry

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Release : 2007-12-04
Genre : Science
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Book Rating : 327/5 ( reviews)

Redox Biochemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Redox Biochemistry write by Ruma Banerjee. This book was released on 2007-12-04. Redox Biochemistry available in PDF, EPUB and Kindle. This is the premier, single-source reference on redox biochemistry, a rapidly emerging field. This reference presents the basic principles and includes detailed chapters focusing on various aspects of five primary areas of redox biochemistry: antioxidant molecules and redox cofactors; antioxidant enzymes; redox regulation of physiological processes; pathological processes related to redox; and specialized methods. This is a go-to resource for professionals in pharmaceuticals, medicine, immunology, nutrition, and environmental fields and an excellent text for upper-level students.

Review of Submarine Escape Action Levels for Selected Chemicals

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Release : 2002-02-04
Genre : Nature
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Book Rating : 689/5 ( reviews)

Review of Submarine Escape Action Levels for Selected Chemicals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Review of Submarine Escape Action Levels for Selected Chemicals write by National Research Council. This book was released on 2002-02-04. Review of Submarine Escape Action Levels for Selected Chemicals available in PDF, EPUB and Kindle. On-board fires can occur on submarines after events such as collision or explosion. These fires expose crew members to toxic concentrations of combustion products such as ammonia, carbon monoxide, hydrogen chloride, and hydrogen sulfide. Exposure to these substances at high concentrations may cause toxic effects to the respiratory and central nervous system; leading possible to death. T protect crew members on disabled submarines, scientists at the U.S. Navy Health Research Center's Toxicology Detachment have proposed two exposure levels, called submarine escape action level (SEAL) 1 and SEAL 2, for each substance. SEAL 1 is the maximum concentration of a gas in a disabled submarine below which healthy submariners can be exposed for up to 10 days without encountering irreversible health effects while SEAL 2 the maximum concentration of a gas in below which healthy submariners can be exposed for up to 24 hours without experiencing irreversible health effects. SEAL 1 and SEAL 2 will not impair the functions of the respiratory system and central nervous system to the extent of impairing the ability of crew members in a disabled submarine to escape, be rescued, or perform specific tasks. Hoping to better protect the safety of submariners, the chief of the Bureau of Medicine and Surgery requested that the National Research Council (NRC) review the available toxicologic and epidemiologic data on eight gases that are likely to be produced in a disabled submarine and to evaluate independently the scientific validity of the Navy's proposed SEALs for those gases. The NRC assigned the task to the Committee on Toxicology's (COT's) Subcommittee on Submarine Escape Action Levels. The specific task of the subcommittee was to review the toxicologic, epidemiologic, and related data on ammonia, carbon monoxide, chlorine, hydrogen chloride, hydrogen cyanide, hydrogen sulfide, nitrogen dioxide, and sulfur dioxide in order to validate the Navy's proposed SEALs. The subcommittee also considered the implications of exposures at hyperbaric conditions and potential interactions between the eight gases. Review of Submarine Escape Action Levels for Selected Chemicals presents the subcommittee's findings after evaluation human data from experimental, occupational, and epidemiologic studies; data from accident reports; and experimental-animal data. The evaluations focused primarily on high-concentration inhalation exposure studies. The subcommittee's recommended SEALs are based solely on scientific data relevant to health effects. The report includes the recommendations for each gas as determined by the subcommittee as well as the Navy's original instructions for these substances.

Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide

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Release : 2015
Genre :
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Book Rating : 455/5 ( reviews)

Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide write by Philip K. Moore. This book was released on 2015. Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide available in PDF, EPUB and Kindle. This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.

Biological Inorganic Chemistry

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Release : 2007
Genre : Science
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Book Rating : 436/5 ( reviews)

Biological Inorganic Chemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Biological Inorganic Chemistry write by Ivano Bertini. This book was released on 2007. Biological Inorganic Chemistry available in PDF, EPUB and Kindle. Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.