Comparative Genomics and Proteomics in Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Comparative Genomics and Proteomics in Drug Discovery write by John Parrington. This book was released on 2018-12-07. Comparative Genomics and Proteomics in Drug Discovery available in PDF, EPUB and Kindle. Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds.
Genomics and Proteomics for Clinical Discovery and Development
Genomics and Proteomics for Clinical Discovery and Development - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Genomics and Proteomics for Clinical Discovery and Development write by György Marko-Varga. This book was released on 2014-08-26. Genomics and Proteomics for Clinical Discovery and Development available in PDF, EPUB and Kindle. The book is intended to be a resource for students as well as scientists in education and for the general public to learn about proteomics and genomics. Chromosomes form the basis for our genetic heritage and are the code for protein synthesis. The Human Genome Map came out in 2002, and the Proteome Sequence Map is under currently being created by a global consortia initiative. Proteome and genome building blocks already form the basis of scientific research areas as well as large parts of the pharmaceutical and biomedical industry. The book initiative will provide the background to and our current understanding of these gene and protein areas, as well as describe how cutting-edge science is using these resources to develop new medicines and new diagnostics for patient care and treatment. The book will be useful for undergraduate students as well as university students and researchers who need a good understanding of genomics and proteomics within the clinical field. The book will also be targeted at a broad public as well as readers not specialized within this field. Dr. Marko-Varga is the head of the Head of Div. Clinical Protein Science & Imaging at the Biomedical Center, Dept. of Measurement Technology and Industrial Electrical Engineering, Lund University, and Professor at the 1st Department of Surgery, Tokyo Medical University, Tokyo, Japan.
Proteomics: Biomedical and Pharmaceutical Applications
Proteomics: Biomedical and Pharmaceutical Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Proteomics: Biomedical and Pharmaceutical Applications write by Hubert Hondermarck. This book was released on 2007-05-08. Proteomics: Biomedical and Pharmaceutical Applications available in PDF, EPUB and Kindle. Human biology has now entered into a phase of post-genomics and it might not be an exaggeration to say that the major outcome of the human genome sequencing has finally been to open the way to the exploration of the proteome-proteomics. Proteins are the functional output of genes and there are two main expected outcomes from human proteomics. The first is to discover new molecular markers for early diagnosis and profiling of pathologies. The second is to decipher the intracellular signaling pathways leading to the initiation and progression of pathologies, for the identification of new targets and the development of innovative therapeutic strategies. This is clearly a promising challenge that this book explores through a series of ongoing experiences and projects representative of the new era in which biology and medicine have now entered.
Bioinformatics: Genomics and Proteomics
Bioinformatics: Genomics and Proteomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Bioinformatics: Genomics and Proteomics write by Singh Ruchi. This book was released on 2015. Bioinformatics: Genomics and Proteomics available in PDF, EPUB and Kindle. This is an innovative textbook for undergraduates as well as postgraduates offering basic knowledge of biology. Its aim is to provide state-of-the-art information about this developing science that has the potential to replace existing biological approaches to study genes and proteins. The chapters are explained in a concise yet detailed manner, including ample cross-references, references to literature and databases, tables and illustrations. The book's sound approach to this intricately complex field makes it an exceptional resource for further exploration into biochemistry, molecular biology, genomics and drug designing fields. Abundant learning features make this book the ideal teaching and learning tool. KEY FEATURES • Illustrations to bolster understanding of complex biochemical relations • Tables for quick access to precise data • Extensive end-of-chapter exercises and references • The most basic details furnished for those who are new to biology • User-friendly, Internet-based bioinformatics tools that allow researchers to extract information from databases and analyze it • Analysis of one software tool discussed in each chapter step-by-step from entering the input till interpretation of the results This is an in-depth textbook written for the biologist who wants a thorough understanding of the popular bioinformatics programs and molecular databases currently in use. It provides a broad, application-oriented overview of this technology.
Comparative Genomics and Drug Design Strategies
Comparative Genomics and Drug Design Strategies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Comparative Genomics and Drug Design Strategies write by Manoj Kumar Yadav. This book was released on 2015-01-31. Comparative Genomics and Drug Design Strategies available in PDF, EPUB and Kindle. Malaria is a threat to mankind and responsible for millions of cases of morbidity and mortality worldwide. Plasmodium parasite is responsible for causing disease. This work investigates and reveals the hidden information inside the parasite genomes using comparative genome analysis and codon usage bias study. The possibility of using variable surface proteins as a common drug target has been checked in both the human infecting Plasmodium species and it was found that variable surface proteins cannot be used as a common drug target due to existence of sequential and structural differences at both the genome and proteome level. Metabolic network information is also utilized in this piece of work for identifying new drug targets. Further in silico approaches viz. molecular modeling, structure-based 3D pharmacophore model generation, virtual screening and docking etc. were also utilized to find the drug prototypes.
