Protein Interaction Networks - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Interaction Networks write by Aidong Zhang. This book was released on 2009-04-06. Protein Interaction Networks available in PDF, EPUB and Kindle. The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Proteins seldom act as single isolated species; rather, proteins involved in the same cellular processes often interact with each other. Functions of uncharacterized proteins can be predicted through comparison with the interactions of similar known proteins. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.
Computational Analysis of Protein-protein Interactions
Computational Analysis of Protein-protein Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Computational Analysis of Protein-protein Interactions write by Sam Ansari. This book was released on 2007. Computational Analysis of Protein-protein Interactions available in PDF, EPUB and Kindle.
Protein Interactions: Computational Methods, Analysis And Applications
Protein Interactions: Computational Methods, Analysis And Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Interactions: Computational Methods, Analysis And Applications write by M Michael Gromiha. This book was released on 2020-03-05. Protein Interactions: Computational Methods, Analysis And Applications available in PDF, EPUB and Kindle. This book is indexed in Chemical Abstracts ServiceThe interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design.This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules.
Protein-protein Interactions and Networks
Protein-protein Interactions and Networks - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein-protein Interactions and Networks write by Anna Panchenko. This book was released on 2010-04-06. Protein-protein Interactions and Networks available in PDF, EPUB and Kindle. The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse data on protein-protein interactions and protein interaction networks.
Protein-Protein Interactions
Protein-Protein Interactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein-Protein Interactions write by Weibo Cai. This book was released on 2012-03-30. Protein-Protein Interactions available in PDF, EPUB and Kindle. Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others.
