Computational Molecular Evolution

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Release : 2006-10-05
Genre : Medical
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Book Rating : 999/5 ( reviews)

Computational Molecular Evolution - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Computational Molecular Evolution write by Ziheng Yang. This book was released on 2006-10-05. Computational Molecular Evolution available in PDF, EPUB and Kindle. This book describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes.

Molecular Evolution

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Release : 2014
Genre : Science
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Book Rating : 603/5 ( reviews)

Molecular Evolution - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Evolution write by Ziheng Yang. This book was released on 2014. Molecular Evolution available in PDF, EPUB and Kindle. Studies of evolution at the molecular level have experienced phenomenal growth in the last few decades, due to rapid accumulation of genetic sequence data, improved computer hardware and software, and the development of sophisticated analytical methods. The flood of genomic data has generated an acute need for powerful statistical methods and efficient computational algorithms to enable their effective analysis and interpretation. Molecular Evolution: a statistical approach presents and explains modern statistical methods and computational algorithms for the comparative analysis of genetic sequence data in the fields of molecular evolution, molecular phylogenetics, statistical phylogeography, and comparative genomics. Written by an expert in the field, the book emphasizes conceptual understanding rather than mathematical proofs. The text is enlivened with numerous examples of real data analysis and numerical calculations to illustrate the theory, in addition to the working problems at the end of each chapter. The coverage of maximum likelihood and Bayesian methods are in particular up-to-date, comprehensive, and authoritative. This advanced textbook is aimed at graduate level students and professional researchers (both empiricists and theoreticians) in the fields of bioinformatics and computational biology, statistical genomics, evolutionary biology, molecular systematics, and population genetics. It will also be of relevance and use to a wider audience of applied statisticians, mathematicians, and computer scientists working in computational biology.

Molecular Evolution and Phylogenetics

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Release : 2000-07-27
Genre : Science
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Book Rating : 227/5 ( reviews)

Molecular Evolution and Phylogenetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Evolution and Phylogenetics write by Masatoshi Nei. This book was released on 2000-07-27. Molecular Evolution and Phylogenetics available in PDF, EPUB and Kindle. During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

Bioinformatics and Molecular Evolution

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Release : 2013-04-30
Genre : Science
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Book Rating : 065/5 ( reviews)

Bioinformatics and Molecular Evolution - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Bioinformatics and Molecular Evolution write by Paul G. Higgs. This book was released on 2013-04-30. Bioinformatics and Molecular Evolution available in PDF, EPUB and Kindle. In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.

Introduction to Computational Biology

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Release : 2006-08-09
Genre : Science
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Book Rating : 873/5 ( reviews)

Introduction to Computational Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Introduction to Computational Biology write by Bernhard Haubold. This book was released on 2006-08-09. Introduction to Computational Biology available in PDF, EPUB and Kindle. Written with the advanced undergraduate in mind, this book introduces into the field of Bioinformatics. The authors explain the computational and conceptional background to the analysis of large-scale sequence data. Many of the corresponding analysis methods are rooted in evolutionary thinking, which serves as a common thread throughout the book. The focus is on methods of comparative genomics and subjects covered include: alignments, gene finding, phylogeny, and the analysis of single nucleotide polymorphisms (SNPs). The volume contains exercises, questions & answers to selected problems.