CRISPR and RNAi Systems

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Release : 2021-02-27
Genre : Technology & Engineering
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Book Rating : 114/5 ( reviews)

CRISPR and RNAi Systems - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook CRISPR and RNAi Systems write by Kamel A Abd-Elsalam. This book was released on 2021-02-27. CRISPR and RNAi Systems available in PDF, EPUB and Kindle. Plants are vulnerable to pathogens including fungi, bacteria, and viruses, which cause critical problems and deficits. Crop protection by plant breeding delivers a promising solution with no obvious effect on human health or the local ecosystem. Crop improvement has been the most powerful approach for producing unique crop cultivars since domestication occurred, making possible the main innovations in feeding the globe and community development. Genome editing is one of the genetic devices that can be implemented, and disease resistance is frequently cited as the most encouraging application of CRISPR/Cas9 technology in agriculture. Nanobiotechnology has harnessed the power of genome editing to develop agricultural crops. Nanosized DNA or RNA nanotechnology approaches could contribute to raising the stability and performance of CRISPR guide RNAs. This book brings together the latest research in these areas. CRISPR and RNAi Systems: Nanobiotechnology Approaches to Plant Breeding and Protection presents a complete understanding of the RNAi and CRISPR/Cas9 techniques for controlling mycotoxins, fighting plant nematodes, and detecting plant pathogens. CRISPR/Cas genome editing enables efficient targeted modification in most crops, thus promising to accelerate crop improvement. CRISPR/Cas9 can be used for management of plant insects, and various plant pathogens. The book is an important reference source for both plant scientists and environmental scientists who want to understand how nano biotechnologically based approaches are being used to create more efficient plant protection and plant breeding systems. - Shows how nanotechnology is being used as the basis for new solutions for more efficient plant breeding and plant protection - Outlines the major techniques and applications of both CRISPR and RNAi technologies - Assesses the major challenges of escalating these technologies on a mass scale

Modulating Gene Expression

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Release : 2019-05-29
Genre : Medical
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Book Rating : 962/5 ( reviews)

Modulating Gene Expression - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Modulating Gene Expression write by Aditi Singh. This book was released on 2019-05-29. Modulating Gene Expression available in PDF, EPUB and Kindle. RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.

Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies

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Release : 2019
Genre : Genetics
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Book Rating : 989/5 ( reviews)

Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies write by Mohammad W. Khan. This book was released on 2019. Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies available in PDF, EPUB and Kindle. RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.

CRISPR-Cas Systems

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Release : 2012-12-13
Genre : Science
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Book Rating : 57X/5 ( reviews)

CRISPR-Cas Systems - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook CRISPR-Cas Systems write by Rodolphe Barrangou. This book was released on 2012-12-13. CRISPR-Cas Systems available in PDF, EPUB and Kindle. CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B

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Release : 2021-04-29
Genre : Science
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Book Rating : 98X/5 ( reviews)

Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B write by . This book was released on 2021-04-29. Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B available in PDF, EPUB and Kindle. Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems Part B, represents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. It is a simple, rapid, precise, and cost-effective tool for genome editing and regulation of a wide range of organisms. It has gained scientific and public attention worldwide. This volume mainly covers insect cell line, protozoans, zebrafish, drosophila, CRISPRi, patents as well as technology transfer, and many more. This book is a key source of information available in a single volume. This book will be useful for not only beginners in genome engineering, but also students, researchers, scientists, policymakers, and stakeholders interested in harnessing the potential of reprogramming of the genomes in several areas. - Offers basic understanding and a clear picture of genome editing CRISPR-Cas systems in different organisms - Explains how to create an animal model for disease diagnosis/research and reprogram CRISPR for insect cell line, protozoans, zebrafish, drosophila, and many more - Discusses the advances, patents, applications, challenges and opportunities in CRISPR-Cas9 systems in basic sciences, biomedicine, molecular biology and many more