CRISPR in Animals and Animal Models - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook CRISPR in Animals and Animal Models write by . This book was released on 2017-11-10. CRISPR in Animals and Animal Models available in PDF, EPUB and Kindle. CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present and future of CRISPR genome editing. Topics of interest in this updated volume include a section on CRISPR history, The genome editing revolution, Programming CRISPR and its applications, CRISPR Delivery methods, CRISPR libraries and screening, CRISPR investigation in haploid cells, CRISPR in the generation of transgenic animals, CRISPR therapeutics, and Promising strategies and present challenges. Accessible to students and researchers alike Written by leading authorities in the field
Cellular and Animal Models in Human Genomics Research
Cellular and Animal Models in Human Genomics Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cellular and Animal Models in Human Genomics Research write by . This book was released on 2019-07-30. Cellular and Animal Models in Human Genomics Research available in PDF, EPUB and Kindle. Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms
Genome Editing Applications in Animal Research
Genome Editing Applications in Animal Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Genome Editing Applications in Animal Research write by Jun Song. This book was released on 2022-02-18. Genome Editing Applications in Animal Research available in PDF, EPUB and Kindle.
Genome Editing in Animals
Genome Editing in Animals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Genome Editing in Animals write by Izuho Hatada. This book was released on 2023-03-11. Genome Editing in Animals available in PDF, EPUB and Kindle. This second edition provides new and updated protocols that can be used for generation of knockout animals. Chapters guide the reader through basic protocols for three genome editing technologies, target design tools, and specific protocols for each animal. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Genome Editing in Animals: Methods and Protocols, Second Edition aims to be a useful practical guide to researches to help further their study in this field.
Viral Pathogenesis
Viral Pathogenesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Viral Pathogenesis write by Michael G. Katze. This book was released on 2015-12-30. Viral Pathogenesis available in PDF, EPUB and Kindle. Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. Covers all aspects of viral infection, including viral entry, replication, and release, as well as innate and adaptive immunity and viral pathogenesis Provides a fresh perspective on the approaches used to understand how viruses cause disease Features molecular profiling techniques, whole genome sequencing, and innovative computational methods Highlights the use of contemporary approaches and the insights they provide to the field
