Curing Genetic Diseases through Genome Reprogramming - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Curing Genetic Diseases through Genome Reprogramming write by . This book was released on 2021-06-24. Curing Genetic Diseases through Genome Reprogramming available in PDF, EPUB and Kindle. Curing Genetic Diseases through Genome Reprogramming, Volume 182 captures an historic moment in the field of gene therapy—the dawn of a new age in which the dream of curing genetic diseases has become realizable. The volume presents the most clinically advanced gene therapy and genome editing approaches for the treatment of genetic diseases in specific organs, including difficult therapeutic targets, futuristic ideas of genetic interventions, and large scale human genome repair. An initial chapter addresses the complex ethical aspects involved in the very idea of modifying the human genome. Provides a comprehensive view of gene therapy and genome editing technologies, including epigenetic editing Describes the state-of-the-art and future directions for the treatment of genetic diseases, also considering economical aspects Presents chapters that each give a thorough review of a specific disease, target organ or visionary approach, including ethical considerations
Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy
Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy write by . This book was released on 2021-06-12. Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy available in PDF, EPUB and Kindle. Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy, presents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 is a key technology for targeted genome editing and regulation in a number of organisms including mammalian cells. It is a rapid, simple, and cost-effective solution. CRISPR-Cas system has recently gained much scientific and public attention. This volume covers CRISPR-Cas9 based mammalian genome editing, creating disease models, cancer therapy, neurological, heredity, blood disorders, defective gene correction, stem cells therapy, epigenetic modifications, patents, ethics, biosafety and regulatory issues challenges and opportunities. This book is a key source of information on mammalian genome editing available in a single volume. This book will be useful for beginners in mammalian genome editing and also students, researchers, scientists, policymakers, clinicians and stakeholders interested in genome editing in several areas. Offers basic understanding and a clear picture of mammalian genome editing through CRISPR-Cas systems Discusses how to create mammalian disease models, stem cell modification, epigenetic modifications, correction of defective gene in blood disorders, heredity, neurological disorders and many more Discusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, molecular biology, translational sciences, neurobiology, neurology, cancer, stem cells, and many more
Gene Therapy
Gene Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Therapy write by Joseph Panno. This book was released on 2005. Gene Therapy available in PDF, EPUB and Kindle. Many diseases are caused by a simple point mutation.
Gene Editing in Plants
Gene Editing in Plants - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Editing in Plants write by . This book was released on 2017-07-14. Gene Editing in Plants available in PDF, EPUB and Kindle. Gene Editing in Plants, Volume 149 aims to provide the reader with an up-to-date survey of cutting-edge research with gene editing tools and an overview of the implications of this research on the nutritional quality of fruits, vegetables and grains. New chapters in the updated volume include topics relating to Genome Engineering and Agriculture: Opportunities and Challenges, the Use of CRISPR/Cas9 for Crop Improvement in Maize and Soybean, the Use of Zinc-Finger Nucleases for Crop Improvement, Gene Editing in Polyploid Crops: Wheat, Camelina, Canola, Potato, Cotton, Peanut, Sugar Cane, and Citrus, and Gene Editing With TALEN and CRISPR/Cas in Rice. This ongoing serial contain contributions from leading scientists and researchers in the field of gene editing in plants who describe the results of their own research in this rapidly expanding area of science. Shows the importance of revolutionary gene editing technology on plant biology research and its application to agricultural production Provides insight into what may lie ahead in this rapidly expanding area of plant research and development Contains contributions from major leaders in the field of plant gene editing
Heritable Human Genome Editing
Heritable Human Genome Editing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Heritable Human Genome Editing write by The Royal Society. This book was released on 2021-01-16. Heritable Human Genome Editing available in PDF, EPUB and Kindle. Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
