Cyclic Peptide Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cyclic Peptide Design write by Gilles Goetz. This book was released on 2019-05-28. Cyclic Peptide Design available in PDF, EPUB and Kindle. This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature’s cyclic peptides and macrocycles. Chapters also cover key peptide screening and display strategies, as well as important synthetic approaches towards cyclic and helical peptides. Cyclic peptides have become of significant importance as chemical tools in biology and drug discovery, since this class of chemicals has become a credible alternative source of new drug leads on par with traditional small molecules. As a part of the Methods in Molecular Biology series, this collection includes the kind of detail and implementation advice to aid researchers in the field. Authoritative and cutting-edge, Cyclic Peptide Design serves as a critical resource and go-to reference for researchers within the pharmaceutical industry, as well as scientists and students in the bioorganic, medicinal, and natural product chemistry fields.
Practical Medicinal Chemistry with Macrocycles
Practical Medicinal Chemistry with Macrocycles - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Practical Medicinal Chemistry with Macrocycles write by Eric Marsault. This book was released on 2017-09-12. Practical Medicinal Chemistry with Macrocycles available in PDF, EPUB and Kindle. Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations
Peptide Macrocycles
Peptide Macrocycles - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptide Macrocycles write by Matthew B. Coppock. This book was released on 2021-11-02. Peptide Macrocycles available in PDF, EPUB and Kindle. This volume explores the latest techniques and strategies used to study the field of peptide macrocycles. The chapters in this book ae organized into four parts: macrocycles synthesis, combinational library synthesis and screening, macrocycle characterization, and unique applications. Part One looks at a variety of peptide cyclization methodologies, and Part Two describes methods for the creation of peptide macrocycles libraries and their subsequent screening against biological targets of interest. Part Three discusses the study and characterization of peptide macrocycle-target interactions, and Part Four introduces unique applications for peptide macrocycles, from higher-order structure formation to post-synthetic functional modifications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Peptide Macrocycles: Methods and Protocols is a valuable resource for both novice and expert researchers looking to learn more about this developing field.
Cyclic Peptides
Cyclic Peptides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cyclic Peptides write by Jesko Koehnke. This book was released on 2017-12-15. Cyclic Peptides available in PDF, EPUB and Kindle. This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.
Conformational Design of Cyclic Peptides
Conformational Design of Cyclic Peptides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Conformational Design of Cyclic Peptides write by Bethany Atkinson. This book was released on 2022. Conformational Design of Cyclic Peptides available in PDF, EPUB and Kindle.
