Cyclic Peptides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cyclic Peptides write by Jesko Koehnke. This book was released on 2017-12-15. Cyclic Peptides available in PDF, EPUB and Kindle. This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.
Cyclic Peptides
Cyclic Peptides - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cyclic Peptides write by Jesko Koehnke. This book was released on 2017-12-14. Cyclic Peptides available in PDF, EPUB and Kindle. Cyclic peptides are increasingly employed as chemical tools in biology and drug discovery. They have gained a lot of interest as alternative sources of new drugs to traditional small molecules. This book introduces cyclic peptides and provides a thorough overview of biosynthetic and fully synthetic approaches to their preparation. Following an introduction to cyclic peptides, biosynthetic and traditional chemical routes to cyclic peptides are reviewed. Due to their size, their synthesis is not trivial. Recent advances in the incorporation of novel structural units are presented in addition to how synthesis and biological methods can be combined. The chemical analysis of this molecular class is also discussed. Furthermore, chapters detail the progression of cyclic peptides as tools in biology and as potential drugs, providing a future vision of their importance. In total, this book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to possible clinical utility. This book will be an essential resource for students, researchers and scientists within industry in medicinal, bioorganic, natural product and analytical chemistry fields.
The Cyclic Peptide Toxins of Amanita and Other Poisonous Mushrooms
The Cyclic Peptide Toxins of Amanita and Other Poisonous Mushrooms - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Cyclic Peptide Toxins of Amanita and Other Poisonous Mushrooms write by Jonathan Walton. This book was released on 2018-05-09. The Cyclic Peptide Toxins of Amanita and Other Poisonous Mushrooms available in PDF, EPUB and Kindle. Poisonous mushrooms have fascinated scientists and laypersons alike for thousands of years. Almost all mushroom fatalities are due to the genus Amanita, whose poetic common names (death cap, destroying angel) attest to their lethality. In his classic 1986 book, Theodor Wieland covered the state of our knowledge about the chemistry and biochemistry of the toxins of Amanita mushrooms up until that time, with a particular focus on the decades of chemical research by him and the Wieland dynasty (including his father, brother, brother-in-law, and cousin). Wieland’s book is now mainly of historical interest, with its exhaustive overview of the early chemical studies done without benefit of methods taken for granted by modern chemists. This book is a complete top-to-bottom revision of Wieland’s 1986 book. The material covers history, chemistry, and biology with equal thoroughness. It should be of interest to natural products chemists and biologists, professional and amateur mycologists, and toxicologists. The three scientific fields that are most relevant to the book are natural products chemistry, mycology, and fungal molecular genetics. Dr. Walton is an expert in all three. To maximize the broad utility and appeal of the book, care has been taken to define all technical terms specific to a particular discipline, so that, for example, mycologists will be able to understand the relevant chemistry, and chemists will be able to understand the relevant fungal biology.
Guide to Electroporation and Electrofusion
Guide to Electroporation and Electrofusion - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Guide to Electroporation and Electrofusion write by Donald Chang. This book was released on 1991-12-11. Guide to Electroporation and Electrofusion available in PDF, EPUB and Kindle. Guide to Electroporation and Electrofusion is designed to cover all relevant topics pertaining to both electroporation and electrofusion. Divided into four major parts, the book covers fundamental aspects, as well as more advance aspects of the electroporation-electrofusion relationship. The book first covers the basic principles and fundamentals by presenting the most recent theoretical and experimental studies from various fields, such as physics, chemistry, and biology. Next, the book tackles the applications of electroporation and electrofusion in biology, such as transferring, manipulating, and transforming genetic materials. In the third section, the book discusses experimental protocols to serve as a guide when performing experiments using electroporation and electrofusion. The final section discusses the instruments needed to effectively perform an experiment that involves electroporation and electrofusion. This book will be of great used to both novice and advanced researchers whose work involves electroporation and electrofusion, as it provides comprehensive information regarding these topics.
Cyclic Peptide Design
Cyclic Peptide Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cyclic Peptide Design write by Gilles Goetz. This book was released on 2019-05-28. Cyclic Peptide Design available in PDF, EPUB and Kindle. This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature’s cyclic peptides and macrocycles. Chapters also cover key peptide screening and display strategies, as well as important synthetic approaches towards cyclic and helical peptides. Cyclic peptides have become of significant importance as chemical tools in biology and drug discovery, since this class of chemicals has become a credible alternative source of new drug leads on par with traditional small molecules. As a part of the Methods in Molecular Biology series, this collection includes the kind of detail and implementation advice to aid researchers in the field. Authoritative and cutting-edge, Cyclic Peptide Design serves as a critical resource and go-to reference for researchers within the pharmaceutical industry, as well as scientists and students in the bioorganic, medicinal, and natural product chemistry fields.
