Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies write by Wojciech Gorczyca. This book was released on 2008-08-01. Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies available in PDF, EPUB and Kindle. Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially polymerase chain reaction (PCR), play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis, as well as predict prognosis, response to treatment and disease progression. Chromosomal and molecular abnormalities provide the most reliable criteria for classification of hematopoietic tumors and often comprise the basis for targeted therapy. Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies, provides a review of chromosomal and molecular changes in hematologic malignancies and correlates the karyotypic and genetic abnormalities with morphology, immunophenotype and clinical data. With over 180 figures and diagnostic algorithms, this text is essential reading for all pathologists, hematopathologists, hematologic oncologists, cytogenetists, cytogenetic technologists and cell biologists.
Hematologic Malignancies
Hematologic Malignancies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hematologic Malignancies write by Manorama Bhargava. This book was released on 2021. Hematologic Malignancies available in PDF, EPUB and Kindle. This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.
Molecular Aspects of Hematologic Malignancies
Molecular Aspects of Hematologic Malignancies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Aspects of Hematologic Malignancies write by Michal Witt. This book was released on 2012-06-30. Molecular Aspects of Hematologic Malignancies available in PDF, EPUB and Kindle. This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
Cancer Cytogenetics
Cancer Cytogenetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cancer Cytogenetics write by John Swansbury. This book was released on 2008-02-05. Cancer Cytogenetics available in PDF, EPUB and Kindle. A collection of key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies. The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias towards anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH.
Atlas of Differential Diagnosis in Neoplastic Hematopathology
Atlas of Differential Diagnosis in Neoplastic Hematopathology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Atlas of Differential Diagnosis in Neoplastic Hematopathology write by Wojciech Gorczyca. This book was released on 2021-10-27. Atlas of Differential Diagnosis in Neoplastic Hematopathology available in PDF, EPUB and Kindle. This atlas presents not only the differential diagnosis but also the detailed morphologic, immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid malignancies. An expert hematopathologist here provides a valuable resource to understand, use, or interpret one or more of these diagnostic modalities with confidence. This new edition has a compact format with up-to-date information - especially on genetic aspects - and will be an indispensable reference for all professionals in the specialty. *Provides an unrivalled visual resource for differential diagnosis in neoplastic hematopathology *Enables specialist and trainee oncologists and pathologists alike to understand, use, and interpret diagnostic modalities with confidence *Supplies quick access to information via tables, algorithms, and composite figures
