Development of New Methods to Synthesize Heterocyclic Compounds - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Development of New Methods to Synthesize Heterocyclic Compounds write by Md Shafaat Al Mehedi. This book was released on 2021. Development of New Methods to Synthesize Heterocyclic Compounds available in PDF, EPUB and Kindle. This dissertation is focused on the development of new methods to synthesize imidazoline scaffolds. The work discusses three new procedures developed in the Tepe lab to synthesize trans-oxazoline, trans-imidazoline, and 2,3-disubstituted quinoline scaffolds. In addition, a new guanidine base mediated diastereoselective aziridine synthesis is described in this work. These new synthetic methodologies provide access to compounds that were not easily accessible using previously described methods. Paths to oxazolines and imidazolines via modified Corey-Chaykovsky sulfur ylide chemistry are presented. Here, the sulfonium salts were treated with stable precursors of acyl imines and 1,3-diaza-1,3-butadiene intermediates, respectively, for the oxazoline and imidazoline syntheses. A modified Skraup-type reaction was employed to synthesize 2,3-disubstituted quinoline scaffolds where epoxides were treated with aromatic anilines under mild conditions in the presence of a Lewis acid.
Advances in Heterocyclic Chemistry
Advances in Heterocyclic Chemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Advances in Heterocyclic Chemistry write by . This book was released on 2020-01-23. Advances in Heterocyclic Chemistry available in PDF, EPUB and Kindle. Advances in Heterocyclic Chemistry, Volume 130, the latest release in this definitive series, provides a comprehensive review that combines descriptive synthetic chemistry and mechanistic insights to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. New chapters in this release include Recent Developments in the Radiolabeling of Heterocyclic Rings, Chemistry of Azetidines, Tricyclic Fused Bithiophenes and Related Analogues: Important Building Blocks for Conjugated Materials, Application of Electrochemical Methods in the Synthesis of Heterocyclic Compounds and Elucidation of Their Properties, Organometallic Complexes of Chelating Azines, and more. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews as written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds
Non-Conventional Synthesis
Non-Conventional Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Non-Conventional Synthesis write by György Keglevich. This book was released on 2023-11-06. Non-Conventional Synthesis available in PDF, EPUB and Kindle. Non-conventional synthetic methods may provide new and green methods for the preparation of bioactive heterocycles. These methods, such as microwave and ultrasound assisted synthesis, biocatalysis, photochemistry and electrosynthesis use less energy and may produce less waste to get the desired products when compared to traditional methods. This book explores the use of these methods when synthesizing various biologically relevant heterocyclic scaffolds. THE SERIES: GREEN BIOACTIVE HETEROCYCLES Heterocycles are a widely utilized group of molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis remains challenging with diffi cult to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop greener synthetic methods for the synthesis of structurally diverse bioactive heterocyclic scaffolds. This series aims to do so, by collecting developments into common themes.
Biosynthesis of Heterocycles
Biosynthesis of Heterocycles - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Biosynthesis of Heterocycles write by Patrizia Diana. This book was released on 2015-01-30. Biosynthesis of Heterocycles available in PDF, EPUB and Kindle. This book describes biosynthetic methods to synthesize heterocycliccompounds, offering a guide for the development of new drugs basedon natural products. The authors explain the role of naturalproducts in chemistry and their formation along with importantanalytical methods and techniques for working withheterocycles. • Covers methods and techniques: isotopic labelling,enzymes and mutants, and pathway identification • Provides a thorough resource of informationspecifically on heterocyclic natural products and their practicalbiosynthetic relevance • Explains the role of natural products in chemistry andtheir formation • Discusses gene cluster identification and the use ofbiogenetic engineering in pharmaceutical application
Modern Green Chemistry and Heterocyclic Compounds
Modern Green Chemistry and Heterocyclic Compounds - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Modern Green Chemistry and Heterocyclic Compounds write by Ravindra S. Shinde. This book was released on 2020-03-31. Modern Green Chemistry and Heterocyclic Compounds available in PDF, EPUB and Kindle. This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.
