Discovering Retroviruses - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Discovering Retroviruses write by Anna Marie Skalka. This book was released on 2018-10-15. Discovering Retroviruses available in PDF, EPUB and Kindle. Approximately eight percent of our DNA contains retroviral sequences that are millions of years old. Through engaging stories of scientific discovery, Anna Marie Skalka explains our evolving knowledge of these ancient denizens of the biosphere and how this understanding has significantly advanced research in genetic engineering, gene delivery systems, and precision medicine. Discovering Retroviruses begins with the pioneer scientists who first encountered these RNA-containing viruses and solved the mystery of their reproduction. Like other viruses, retroviruses invade the cells of a host organism to reproduce. What makes them “retro” is a unique process of genetic information transfer. Instead of transcribing DNA into RNA as all living cells do, they transcribe their RNA into DNA. This viral DNA is then spliced into the host’s genome, where the cell’s synthetic machinery is co-opted to make new virus particles. The 100,000 pieces of retroviral DNA in the human genome are remnants from multiple invasions of our ancestors’ “germline” cells—the cells that allow a host organism to reproduce. Most of these bits of retroviral DNA are degenerated fossils, but some have been exploited during evolution, with profound effects on our physiology. Some present-day circulating retroviruses cause cancers in humans and other animals. Others, like HIV, cause severe immunodeficiencies. But retroviruses also hold clues to innovative approaches that can prevent and treat these diseases. In laboratories around the world, retroviruses continue to shed light on future possibilities that are anything but “retro.”
Retroviruses
Retroviruses - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Retroviruses write by John M. Coffin. This book was released on 1997. Retroviruses available in PDF, EPUB and Kindle. For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.
Human Retroviruses
Human Retroviruses - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Human Retroviruses write by Bryan Cullen. This book was released on 1993. Human Retroviruses available in PDF, EPUB and Kindle. The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Virus Hunting
Virus Hunting - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Virus Hunting write by Robert C. Gallo. This book was released on 1991-05-15. Virus Hunting available in PDF, EPUB and Kindle. Examines the discovery of AIDS and other notable discoveries, Gallo's investigation by the NIH, and provides a personal chronicle of the scientist's life.
Retroviruses
Retroviruses - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Retroviruses write by Reinhard Kurth. This book was released on 2010. Retroviruses available in PDF, EPUB and Kindle.
