Dissecting Neuronal Specification in the Drosophila Taste System - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Dissecting Neuronal Specification in the Drosophila Taste System write by Lisa Marie Dennison. This book was released on 2012. Dissecting Neuronal Specification in the Drosophila Taste System available in PDF, EPUB and Kindle. Establishing a complex brain and nervous system requires a wide array of neurons with diverse forms, functions, and characteristics. Developing nervous systems employ many strategies to create this neuronal diversity, and these strategies remain the subject of ongoing investigations in developmental neuroscience. Neuronal diversity in the taste system of Drosophila melanogaster is important for the appropriate detection of chemosensory signals in the fly's environment. Drosophila can distinguish sweet substances, bitter compounds, pheromones, and pure water using distinct populations of taste neurons. The correct detection of such substances is critical for correct ingestion of nutritive foods, avoidance of toxins, recognition of appropriate mates, and hydration, all of which are essential for the survival and propagation of the fly. The first part of this thesis focuses on the developmental relationship between these classes of neurons and the signaling pathways used to diversify them. Mosaic analysis revealed at least two stereotyped lineages for taste neurons innervating bristles on the proboscis of the fly. Furthermore, mutant mosaic studies showed that Numb inheritance or lack thereof is necessary for correct cell fate decisions. The involvement of Numb strongly indicates that Notch signaling is the key player in establishing taste neuron diversity. The second part of this thesis describes an expression screen for transcription factors with specific expression patterns in subsets of taste neurons. The transcription factors activated in each cell type ultimately establish that cell's unique identity by activating expression of appropriate receptors, axon guidance cues, neurotransmitters, and more. The screen identified two transcription factors, knot and Lim3, with specific expression in bitter-sensing neurons. Results of loss-of-function and gain-of-function studies with each gene indicate that neither one alone is necessary or sufficient to specify the full bitter neuron fate, but it remains possible that each could play a role in subsets of the bitter neuron's identity not observed by these analyses.
Neurobiology of Chemical Communication
Neurobiology of Chemical Communication - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurobiology of Chemical Communication write by Carla Mucignat-Caretta. This book was released on 2014-02-14. Neurobiology of Chemical Communication available in PDF, EPUB and Kindle. Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism—ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their presence to members of the same species and to regulate interactions aimed at establishing and regulating social and reproductive bonds. In the last two decades, scientists have developed a greater understanding of the neural processing of these chemical signals. Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans. The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones. An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.
Brain Development in Drosophila melanogaster
Brain Development in Drosophila melanogaster - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Brain Development in Drosophila melanogaster write by Gerhard Martin Technau. This book was released on 2009-01-08. Brain Development in Drosophila melanogaster available in PDF, EPUB and Kindle. The fruitfly Drosophila melanogaster is an ideal model system to study processes of the central nervous system This book provides an overview of some major facets of recent research on Drosophila brain development.
Peptidomics
Peptidomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptidomics write by Mikhail Soloviev. This book was released on 2007-12-21. Peptidomics available in PDF, EPUB and Kindle. The definitive guide to peptidomics- a hands-on lab reference The first truly comprehensive book about peptidomics for protein and peptide analysis, this reference provides a detailed description of the hows and whys of peptidomics and how the techniques have evolved. With chapters contributed by leading experts, it covers naturally occurring peptides, peptidomics methods and new developments, and the peptidomics approach to biomarker discovery. Explaining both the principles and the applications, Peptidomics: Methods and Applications: * Features examples of applications in diverse fields, including pharmaceutical science, toxicity biomarkers, and neuroscience * Details the successful peptidomic analyses of biological material ranging from plants to mammals * Describes a cross section of analytical techniques, including traditional methodologies, emerging trends, and new techniques for high throughput approaches An enlightening reference for experienced professionals, this book is sufficiently detailed to serve as a step-by-step guide for beginning researchers and an excellent resource for students taking biotechnology and proteomics courses. It is an invaluable reference for protein chemists and biochemists, professionals and researchers in drug and biopharmaceutical development, analytical and bioanalytical chemists, toxicologists, and others.
Behavioral Genetics of the Fly (Drosophila Melanogaster)
Behavioral Genetics of the Fly (Drosophila Melanogaster) - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Behavioral Genetics of the Fly (Drosophila Melanogaster) write by Josh Dubnau. This book was released on 2014-06-26. Behavioral Genetics of the Fly (Drosophila Melanogaster) available in PDF, EPUB and Kindle. A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.
