DNA Modifications in the Brain - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook DNA Modifications in the Brain write by Timothy W Bredy. This book was released on 2016-12-23. DNA Modifications in the Brain available in PDF, EPUB and Kindle. DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease. Provides a comprehensive overview of the many facets of DNA modifications Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels Contains contributions by influential leaders in the field Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance
Epigenetics, Brain and Behavior
Epigenetics, Brain and Behavior - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Epigenetics, Brain and Behavior write by Paolo Sassone Corsi. This book was released on 2012-10-19. Epigenetics, Brain and Behavior available in PDF, EPUB and Kindle. Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molcular mechanisms implicated in epigentic control and how these may operte in concert. It will be critical to unravel how specifity is achieved. The focus of this volume is on critical epigenetic regulation and chromatin remodeling events that occur in the nervous system and on the presumed mechanisms that operate within neurons to translate them into long-lasting neuronal responses.
Brain's Hidden Switches
Brain's Hidden Switches - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Brain's Hidden Switches write by Veron. This book was released on 2024-05-09. Brain's Hidden Switches available in PDF, EPUB and Kindle. Brain's Hidden Switches: Beyond DNA Our understanding of the brain has traditionally focused on DNA, the blueprint of life. However, recent research unveils a fascinating truth - DNA is just the first act in the grand play of brain function. Beyond the rigid code of genes lies a hidden layer of control - epigenetic mechanisms that act as the brain's hidden switches, dynamically fine-tuning its operations. Imagine a beautifully composed symphony. The sheet music (DNA) outlines the melody and harmony, but the conductor (epigenetics) brings the music to life, adjusting tempo, volume, and individual instrument contributions to create a nuanced and dynamic performance. This analogy aptly describes the interplay between DNA and epigenetics in the brain. Epigenetics, literally meaning "above genetics," refers to modifications that influence gene expression without altering the underlying DNA sequence. These modifications act like dimmer switches on genes, controlling how much protein (the functional output of genes) is produced in different brain regions and throughout an organism's lifespan. There are two key epigenetic mechanisms at play: DNA methylation and histone modifications. DNA methylation involves adding a chemical tag to DNA, often silencing gene activity. Conversely, histone modifications loosen or tighten the packaging of DNA around proteins called histones. Tightly packed DNA is less accessible for protein production, while looser packaging allows for increased gene expression.
Brain, Behavior and Epigenetics
Brain, Behavior and Epigenetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Brain, Behavior and Epigenetics write by Arturas Petronis. This book was released on 2011-05-19. Brain, Behavior and Epigenetics available in PDF, EPUB and Kindle. Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions? Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease? If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment? Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.
Environmental Epigenetics
Environmental Epigenetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Environmental Epigenetics write by L. Joseph Su. This book was released on 2015-05-18. Environmental Epigenetics available in PDF, EPUB and Kindle. This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.
