Structure-based Design of Drugs and Other Bioactive Molecules - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Structure-based Design of Drugs and Other Bioactive Molecules write by Arun K. Ghosh. This book was released on 2014-08-11. Structure-based Design of Drugs and Other Bioactive Molecules available in PDF, EPUB and Kindle. Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design. This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for a given drug target for which a high-resolution structure exists. The authors use numerous examples of recently developed drugs to present "best practice" methods in structurebased drug design with both newcomers and practicing researchers in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design. This book is aimed at new and active medicinal chemists, biochemists, pharmacologists, natural product chemists and those working in drug discovery in the pharmaceutical industry. It is highly recommended as a desk reference to guide students in medicinal and chemical sciences as well as to aid researchers engaged in drug design today.
Tactics in Contemporary Drug Design
Tactics in Contemporary Drug Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Tactics in Contemporary Drug Design write by Nicholas A. Meanwell. This book was released on 2014-12-08. Tactics in Contemporary Drug Design available in PDF, EPUB and Kindle. Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design
Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design write by Adriano D. Andricopulo. This book was released on 2019-02-05. Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design available in PDF, EPUB and Kindle. Chemoinformatics is paramount to current drug discovery. Structure- and ligand-based drug design strategies have been used to uncover hidden patterns in large amounts of data, and to disclose the molecular aspects underlying ligand-receptor interactions. This Research Topic aims to share with a broad audience the most recent trends in the use of chemoinformatics in drug design. To that end, experts in all areas of drug discovery have made their knowledge available through a series of articles that report state-of-the-art approaches. Readers are provided with outstanding contributions focusing on a wide variety of topics which will be of great value to those interested in the many different and exciting facets of drug design.
Drug Design Strategies
Drug Design Strategies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drug Design Strategies write by David J. Livingstone. This book was released on 2012. Drug Design Strategies available in PDF, EPUB and Kindle. This book brings together drug design practitioners, all leaders in their field, who are actively advancing the field of quantitative methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the fields of bioinformatics and systems biology. The aim of the book is to show how various facets of the drug discovery process can be addressed in a quantitative fashion (ie: numerical analysis to enable robust predictions to be made). Each chapter includes a brief review of the topic showing the historical development of.
Drug Design Strategies
Drug Design Strategies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drug Design Strategies write by Lee Banting. This book was released on 2012. Drug Design Strategies available in PDF, EPUB and Kindle. This book, aimed at academics, industrialists and post-graduates, documents the latest research into computer aided drug design.
