Electroporation-Based Therapies for Cancer

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Author :
Release : 2014-08-28
Genre : Medical
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Book Rating : 298/5 ( reviews)

Electroporation-Based Therapies for Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Electroporation-Based Therapies for Cancer write by Raji Sundararajan. This book was released on 2014-08-28. Electroporation-Based Therapies for Cancer available in PDF, EPUB and Kindle. Electroporation-Based Therapies for Cancer reviews electroporation-based clinical studies in hospitals for various cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and chemo-resistant cancers, that do not respond well to current treatment regimen. An electrical-pulse-mediated, enhanced drug delivery technique known as electroporation is one way to effectively treat these patients. This technique is especially suitable for low- and middle-income countries, where lack of infrastructure and resources leads to cancer diagnoses at late stages. This quick, safe, effective, economical, out-patient-based technique is a boon to these patients for palliative and other care with enhanced quality of life. This book features discussions by interdisciplinary authors—including practicing oncological surgeons, medical professionals, and academic and other researchers—of the basics and clinical medical applications of electroporation. Provides novel and recent clinical applications of electrochemotherapy for various cancers, including melanomas, sarcomas, superficial extreme melanoma, chest wall breast carcinoma, and colorectal cancers Extensive study of a number of cell lines, including human breast cancer, lung cancer, cervical cancer, leukemia, and mouse breast cancer using both reversible and irreversible electroporation techniques In vitro study of delivery of various commonly prescribed/administered breast cancer chemo and hormone drugs, such as Doxorubicin, Paclitaxel, Bleomycin, and Tamoxifen

Electroporation-Based Therapies for Cancer: From Basics to Clinical Applications

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Release : 2017-11-13
Genre : Medical
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Book Rating : 278/5 ( reviews)

Electroporation-Based Therapies for Cancer: From Basics to Clinical Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Electroporation-Based Therapies for Cancer: From Basics to Clinical Applications write by Raji Sundararajan. This book was released on 2017-11-13. Electroporation-Based Therapies for Cancer: From Basics to Clinical Applications available in PDF, EPUB and Kindle. "Electroporation-Based Therapies for Cancer" reviews electroporation-based clinical studies in hospitals for various cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and chemo-resistant cancers, that do not respond well to current treatment regimen. An electrical-pulse-mediated, enhanced drug delivery technique known as electroporation is one way to effectively treat these patients. This technique is especially suitable for low- and middle-income countries, where lack of infrastructure and resources leads to cancer diagnoses at late stages. This quick, safe, effective, economical, out-patient-based technique is a boon to these patients for palliative and other care with enhanced quality of life. This book features discussions by interdisciplinary authors including practicing oncological surgeons, medical professionals, and academic and other researchers of the basics and clinical medical applications of electroporation. Provides novel and recent clinical applications of electrochemotherapy for various cancers, including melanomas, sarcomas, superficial extreme melanoma, chest wall breast carcinoma, and colorectal cancersExtensive study of a number of cell lines, including human breast cancer, lung cancer, cervical cancer, leukemia, and mouse breast cancer using both reversible and irreversible electroporation techniquesIn vitro study of delivery of various commonly prescribed/administered breast cancer chemo and hormone drugs, such as Doxorubicin, Paclitaxel, Bleomycin, and Tamoxifen"

Electroporation in Veterinary Oncology Practice

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Release : 2021-11-20
Genre : Medical
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Book Rating : 685/5 ( reviews)

Electroporation in Veterinary Oncology Practice - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Electroporation in Veterinary Oncology Practice write by Joseph A. Impellizeri. This book was released on 2021-11-20. Electroporation in Veterinary Oncology Practice available in PDF, EPUB and Kindle. This is the first edited collection on veterinary applications of electroporation. Written by an international team of experts, this book presents worldwide emerging therapy options for cancer treatments in veterinary oncology practice. Electroporation offers a precision tool to target cancer cells without destroying surrounding tissue structures. The opening of tumor cell membranes facilitates local control of solid tumors either through the delivery of chemotherapeutics or by direct ablation of tissues using electric fields. In addition, transfer of gene-based products into the cancer cells can be used for genetic vaccination to achieve systemic responses and cancer control. Readers will discover valuable reference texts for practitioner education, including chapters on electrodes for unique anatomical access and treatment planning for deep-seated tumors, different immunotherapy applications with gene electrotransfer, calcium electroporation, irreversible electroporation applications and combinations with other common treatments such as surgery, radiation therapy and chemotherapy. Therapy options with electroporation are gaining interest around the world in both human and veterinary oncology, making this book valuable for oncologists, surgeons, primary care veterinarians, residents, interns and students at veterinary schools, where teaching of Electrochemotherapy will become part of the curriculum. Featuring cross-disciplinary authorship, this work further contributes to advances in comparative medicine and translation research in support of the One Health concept.

Electroporation-based Therapies for Cancer

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Author :
Release : 2014
Genre : Cancer
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Book Rating : /5 ( reviews)

Electroporation-based Therapies for Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Electroporation-based Therapies for Cancer write by Raji Sundararajan. This book was released on 2014. Electroporation-based Therapies for Cancer available in PDF, EPUB and Kindle.

Irreversible Electroporation

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Release : 2009-11-25
Genre : Technology & Engineering
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Book Rating : 20X/5 ( reviews)

Irreversible Electroporation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Irreversible Electroporation write by Boris Rubinsky. This book was released on 2009-11-25. Irreversible Electroporation available in PDF, EPUB and Kindle. Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes – in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.