Scientific Frontiers in Developmental Toxicology and Risk Assessment - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Scientific Frontiers in Developmental Toxicology and Risk Assessment write by National Research Council. This book was released on 2000-12-21. Scientific Frontiers in Developmental Toxicology and Risk Assessment available in PDF, EPUB and Kindle. Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Reducing Birth Defects
Reducing Birth Defects - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Reducing Birth Defects write by Institute of Medicine. This book was released on 2003-10-27. Reducing Birth Defects available in PDF, EPUB and Kindle. Each year more than 4 million children are born with birth defects. This book highlights the unprecedented opportunity to improve the lives of children and families in developing countries by preventing some birth defects and reducing the consequences of others. A number of developing countries with more comprehensive health care systems are making significant progress in the prevention and care of birth defects. In many other developing countries, however, policymakers have limited knowledge of the negative impact of birth defects and are largely unaware of the affordable and effective interventions available to reduce the impact of certain conditions. Reducing Birth Defects: Meeting the Challenge in the Developing World includes descriptions of successful programs and presents a plan of action to address critical gaps in the understanding, prevention, and treatment of birth defects in developing countries. This study also recommends capacity building, priority research, and institutional and global efforts to reduce the incidence and impact of birth defects in developing countries.
Heritable Human Genome Editing
Heritable Human Genome Editing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Heritable Human Genome Editing write by The Royal Society. This book was released on 2021-01-16. Heritable Human Genome Editing available in PDF, EPUB and Kindle. Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Environment and Birth Defects
Environment and Birth Defects - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Environment and Birth Defects write by James Graves Wilson. This book was released on 1973. Environment and Birth Defects available in PDF, EPUB and Kindle.
The Genetics of African Populations in Health and Disease
The Genetics of African Populations in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Genetics of African Populations in Health and Disease write by Muntaser E. Ibrahim. This book was released on 2019-12-19. The Genetics of African Populations in Health and Disease available in PDF, EPUB and Kindle. A pioneering work that focuses on the unique diversity of African genetics, offering insights into human biology and genetic approaches.
