Engineering the Microbial Platform for the Production of Biologics and Small-Molecule Medicines - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Engineering the Microbial Platform for the Production of Biologics and Small-Molecule Medicines write by Dipesh Dhakal. This book was released on 2019-12-23. Engineering the Microbial Platform for the Production of Biologics and Small-Molecule Medicines available in PDF, EPUB and Kindle.
Microbial Cell Factories Engineering for Production of Biomolecules
Microbial Cell Factories Engineering for Production of Biomolecules - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Microbial Cell Factories Engineering for Production of Biomolecules write by Vijai Singh. This book was released on 2021-02-13. Microbial Cell Factories Engineering for Production of Biomolecules available in PDF, EPUB and Kindle. Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs
Continuous Manufacturing for the Modernization of Pharmaceutical Production
Continuous Manufacturing for the Modernization of Pharmaceutical Production - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Continuous Manufacturing for the Modernization of Pharmaceutical Production write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2019-04-05. Continuous Manufacturing for the Modernization of Pharmaceutical Production available in PDF, EPUB and Kindle. On July 30-31, 2018, the National Academies of Sciences, Engineering, and Medicine held a workshop titled Continuous Manufacturing for the Modernization of Pharmaceutical Production. This workshop discussed the business and regulatory concerns associated with adopting continuous manufacturing techniques to produce biologics such as enzymes, monoclonal antibodies, and vaccines. The participants also discussed specific challenges for integration across the manufacturing system, including upstream and downstream processes, analytical techniques, and drug product development. The workshop addressed these challenges broadly across the biologics domain but focused particularly on drug categories of greatest FDA and industrial interest such as monoclonal antibodies and vaccines. This publication summarizes the presentations and discussions from the workshop.
Engineering the Plant Factory for the Production of Biologics and Small-Molecule Medicines
Engineering the Plant Factory for the Production of Biologics and Small-Molecule Medicines - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Engineering the Plant Factory for the Production of Biologics and Small-Molecule Medicines write by Domenico De Martinis. This book was released on 2017-04-27. Engineering the Plant Factory for the Production of Biologics and Small-Molecule Medicines available in PDF, EPUB and Kindle. Plant gene transfer achieved in the early ‘80s paved the way for the exploitation of the potential of gene engineering to add novel agronomic traits and/or to design plants as factories for high added value molecules. For this latter area of research, the term "Molecular Farming" was coined in reference to agricultural applications in that major crops like maize and tobacco were originally used basically for pharma applications. The concept of the “green biofactory” implies different advantages over the typical cell factories based on animal cell or microbial cultures already when considering the investment and managing costs of fermenters. Although yield, stability, and quality of the molecules may vary among different heterologous systems and plants are competitive on a case-to-case basis, still the “plant factory” attracts scientists and technologists for the challenging features of low production cost, product safety and easy scale up. Once engineered, a plant is among the cheapest and easiest eukaryotic system to be bred with simple know-how, using nutrients, water and light. Molecules that are currently being produced in plants vary from industrial and pharmaceutical proteins, including medical diagnostics proteins and vaccine antigens, to nutritional supplements such as vitamins, carbohydrates and biopolymers. Convergence among disciplines as distant as plant physiology and pharmacology and, more recently, as omic sciences, bioinformatics and nanotechnology, increases the options of research on the plant cell factory. “Farming for Pharming” biologics and small-molecule medicines is a challenging area of plant biotechnology that may break the limits of current standard production technologies. The recent success on Ebola fighting with plant-made antibodies put a spotlight on the enormous potential of next generation herbal medicines made especially in the name of the guiding principle of reduction of costs, hence reduction of disparities of health rights and as a tool to guarantee adequate health protection in developing countries.
Engineering the Plant Biofactory for the Production of Biologics and Small-Molecule Medicines - Volume 2
Engineering the Plant Biofactory for the Production of Biologics and Small-Molecule Medicines - Volume 2 - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Engineering the Plant Biofactory for the Production of Biologics and Small-Molecule Medicines - Volume 2 write by Domenico De Martinis. This book was released on 2022-08-03. Engineering the Plant Biofactory for the Production of Biologics and Small-Molecule Medicines - Volume 2 available in PDF, EPUB and Kindle.
