Explicating the relationship between Infections and Alzheimer’s Disease (AD) Etiology, especially Late-onset AD (LOAD). - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Explicating the relationship between Infections and Alzheimer’s Disease (AD) Etiology, especially Late-onset AD (LOAD). write by Dr.H.K.Saboowala.. This book was released on 2020-09-23. Explicating the relationship between Infections and Alzheimer’s Disease (AD) Etiology, especially Late-onset AD (LOAD). available in PDF, EPUB and Kindle. Explicating the relationship between Infections and Alzheimer’s Disease (AD) Etiology, especially Late-onset AD (LOAD). Inflammation is a part of the first line of defense of the body against invasive pathogens and plays a crucial role in tissue regeneration and repair. A proper inflammatory response ensures the suitable resolution of inflammation and elimination of harmful stimuli, but when the inflammatory reactions are inappropriate it can lead to damage of the surrounding normal cells. The relationship between infections and Alzheimer’s Disease (AD) etiology, especially late-onset AD (LOAD) has been continuously debated over the past three decades. Among bacteria special attention is focused on spirochetes family and on periodontal pathogens such as Porphyromonas gingivalis or Treponema denticola that could cause chronic periodontitis and possibly contribute to the clinical onset of AD. Emerging evidence supports the hypothesis of the role of neurotropic viruses from the Herpesviridae family, especially Human herpesvirus 1 (HHV-1), Cytomegalovirus (CMV), and Human herpesvirus 2 (HHV-2), in AD neuropathology. Recent investigations also indicate the association between Hepatitis C virus (HCV) infection and dementia. An attempt has been made to discuss whether infections could be a causative factor that promotes the progression of AD along with Preventive and therapeutic approaches to AD in the context of an infectious etiology of the disease and summarize recent investigations associating infectious agents and chronic inflammation with AD. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Handbook of Infection and Alzheimer's Disease
Handbook of Infection and Alzheimer's Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Handbook of Infection and Alzheimer's Disease write by J. Miklossy. This book was released on 2017-03-10. Handbook of Infection and Alzheimer's Disease available in PDF, EPUB and Kindle. Alzheimer’s disease is one of the biggest emerging public health problems in the world. Although the last four decades have yielded important insights into the pathogenesis of Alzheimer’s disease, its cause is still unclear, and if it is not discovered the world will face an unprecedented healthcare problem by the middle of this century. In recent years, evidence of the microbial origin of various chronic inflammatory disorders – including several neurodegenerative, neuropsychiatric and other systemic disorders – has been steadily growing. Accumulating new and historic observations are providing evidence of an association between Alzheimer’s disease and certain infectious agents, and may offer new opportunities for ground-breaking healthcare solutions. This handbook assembles and connects findings with regard to the infectious origin of Alzheimer’s disease, and the data presented in its chapters deserves the attention of the neuroscience community, physicians and the health departments of governments worldwide by virtue of its amount and quality. This handbook offers a comprehensive overview of the current knowledge regarding the topic of infection and Alzheimer’s disease, which could pinpoint the cause of this disease. Influential diagnosis, treatment and prevention strategies may also emerge from this crucial research area.
Apolipoprotein E and Alzheimer’s Disease
Apolipoprotein E and Alzheimer’s Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Apolipoprotein E and Alzheimer’s Disease write by A.D. Roses. This book was released on 2012-12-06. Apolipoprotein E and Alzheimer’s Disease available in PDF, EPUB and Kindle. There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new filed, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic management of Alzheimer's disease.
Neurodegeneration and Alzheimer's Disease
Neurodegeneration and Alzheimer's Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurodegeneration and Alzheimer's Disease write by Ralph N. Martins. This book was released on 2019-07-10. Neurodegeneration and Alzheimer's Disease available in PDF, EPUB and Kindle. Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.
Neurotoxicity of Metals
Neurotoxicity of Metals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurotoxicity of Metals write by Michael Aschner. This book was released on 2017-09-18. Neurotoxicity of Metals available in PDF, EPUB and Kindle. Assembles international authorities to address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease.
