From Medical Chemistry to Biochemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook From Medical Chemistry to Biochemistry write by Robert E. Kohler. This book was released on 1982-05-31. From Medical Chemistry to Biochemistry available in PDF, EPUB and Kindle. This penetrating case study of institution building and entrepreneurship in science shows how a minor medical speciality evolved into a large and powerful academic discipline. Drawing extensively on little-used archival sources, the author analyses in detail how biomedical science became a central part of medical training and practice. The book shows how biochemistry was defined as a distinct discipline by the programmatic vision of individual biochemists and of patrons and competitors in related disciplines. It shows how discipline builders used research programmes as strategies that they adapted to the opportunities offered by changing educational markets and national medical reform movements in the United States, Britain and Germany. The author argues that the priorities and styles of various departments and schools of biochemistry reflect systematic social relationships between that discipline and biology, chemistry and medicine. Science is shaped by its service roles in particular local contexts: This is the central theme. The author's view of the political economy of modern science will be of interest to historians and social scientists, scientific and medical practitioners, and anyone interested in the ecology of knowledge in scientific institutions and professions.
Medicinal Chemistry
Medicinal Chemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Medicinal Chemistry write by Thomas Nogrady. This book was released on 2005-08-11. Medicinal Chemistry available in PDF, EPUB and Kindle. Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.
Natural Products
Natural Products - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Natural Products write by Goutam Brahmachari. This book was released on 2009. Natural Products available in PDF, EPUB and Kindle. Natural Products provides an insight into significant developments in some of the promising areas of natural products chemistry. Natural products are of great interest and promise in the present day research directed towards drug design and discovery. This book brings together leading scientists of the world, an overview of current discoveries and trends in this remarkable field. The topics, ranging from natural products chemistry and phytochemistry in their most basic form to molecular biology, pharmacology and in silico drug design, summarize years of extensive research in each area, and provide insight in the new themes of natural products research. The book serves as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations; it also motivates young scientists to the dynamic field of bioactive natural products research.
Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide
Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide write by Philip K. Moore. This book was released on 2015-07-10. Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide available in PDF, EPUB and Kindle. This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.
Medical Biochemistry
Medical Biochemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Medical Biochemistry write by John Baynes. This book was released on 2009-03-01. Medical Biochemistry available in PDF, EPUB and Kindle. Medical Biochemistry combines basic science and clinical medicine in a thorough yet accessible, easy-to-read format, and this new edition reflects the latest information on genetic and molecular biology. A new chapter and additional online case studies cover new areas in the field and help clarify difficult concepts. You’ll still get the dynamic, full-color design that makes this biochemistry textbook such an effective resource - complete with case histories, advanced concept boxes, and color illustrations. And, as a Student Consult title, it is fully searchable online with a unique image library, case studies, USMLE-style questions, and online note-taking to enhance your learning experience. Demonstrates the relevance of biochemistry to practice through Clinical Boxes integrated into the text. Provides in-depth coverage of important topics in Advanced Concept Boxes on recent research and more. Explains difficult concepts by working through online case studies that help you apply basic knowledge to clinical practice. Presents the most common lab tests in Clinical Test Boxes that makes referencing and reviewing quick and easy. Offers Active Learning Boxes to allow you to test your knowledge at the end of each chapter and improve retention. Features a new chapter on Genome, Proteome and Metabolome for the latest coverage of these new areas in biochemistry, as well as one on Carbohydrates and Lipids. Includes expanded material on molecular biology to present the nuances of the subject and address those questions that arise during research. Presents 25 additional Case Studies and MCQ’s online with questions and answers that reinforce the material covered.
