Gene Therapy - From Laboratory To The Clinic - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Therapy - From Laboratory To The Clinic write by Kam M Hui. This book was released on 1994-11-29. Gene Therapy - From Laboratory To The Clinic available in PDF, EPUB and Kindle. With advances in our understanding of the molecular biology of human diseases and the development of efficient gene transfer techniques, the treatment of such diseases as cancer and infectious disease using gene therapy has progressed from a distant prospect to a distinct possibility in a very short time. The development of gene transfer methods which are suitable for different forms of therapy has been a major topic of research over the past several years. A common goal of this research has been to achieve the efficient delivery of genes into cells. The successful implementation of gene transfer as a cure for diseases, however, will continue to require the translation of preclinical studies in gene therapy into effective clinical protocols. This volume outlines the latest developments in cancer treatment using various gene delivery systems, which include cytokine gene transfer, the delivery of anti-ras DNA by retroviral vector and the injection of allogeneic HLA DNA via liposomes. Several of these molecular approaches have recently been approved by the US FDA as human clinical trial protocols in order to assess their therapeutic efficiency and safety for cancer treatment. Further developments in recombinant DNA technology within this field should ultimately lead to dramatic improvements in the practice of medicine.
Gene Therapy Technologies, Applications and Regulations
Gene Therapy Technologies, Applications and Regulations - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Therapy Technologies, Applications and Regulations write by Anthony Meager. This book was released on 1999-11-05. Gene Therapy Technologies, Applications and Regulations available in PDF, EPUB and Kindle. This text brings together the current data previously separated. It combines information on gene therapy technologies and the attendant regulatory requirements for gene therapy, products and procedures.
Exploring Novel Clinical Trial Designs for Gene-Based Therapies
Exploring Novel Clinical Trial Designs for Gene-Based Therapies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Exploring Novel Clinical Trial Designs for Gene-Based Therapies write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2020-08-27. Exploring Novel Clinical Trial Designs for Gene-Based Therapies available in PDF, EPUB and Kindle. Recognizing the potential design complexities and ethical issues associated with clinical trials for gene therapies, the Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine held a 1-day workshop in Washington, DC, on November 13, 2019. Speakers at the workshop discussed patient recruitment and selection for gene-based clinical trials, explored how the safety of new therapies is assessed, reviewed the challenges involving dose escalation, and spoke about ethical issues such as informed consent and the role of clinicians in recommending trials as options to their patients. The workshop also included discussions of topics related to gene therapies in the context of other available and potentially curative treatments, such as bone marrow transplantation for hemoglobinopathies. This publication summarizes the presentation and discussion of the workshop.
Gene Therapy
Gene Therapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Therapy write by Mauro Giacca. This book was released on 2010-11-01. Gene Therapy available in PDF, EPUB and Kindle. I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.
Gene Therapy in the Treatment of Cancer
Gene Therapy in the Treatment of Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Therapy in the Treatment of Cancer write by Brian E. Huber. This book was released on 1998-09-24. Gene Therapy in the Treatment of Cancer available in PDF, EPUB and Kindle. The clinical applications of human gene therapy have been particularly fruitful in oncology, and in the past two decades there has been explosive growth in understanding of the genetic lesions leading to neoplasia. This volume in the series Cancer: Clinical Science in Practice reviews progress in the basic and clinical science of gene therapy in oncology, and looks toward future developments. It considers what has worked and what has not in the fast-evolving field of gene therapy, drawing on laboratory studies and clinical trials, including the ground-breaking work of the contributors themselves. Up to date and authoritative, the volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.
