Genetic Control of Malaria and Dengue - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Genetic Control of Malaria and Dengue write by Zach N. Adelman. This book was released on 2015-10-15. Genetic Control of Malaria and Dengue available in PDF, EPUB and Kindle. Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission Provides a summary of the concepts of both population suppression and population replacement Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies
Gene Drives on the Horizon
Gene Drives on the Horizon - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Drives on the Horizon write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2016-08-28. Gene Drives on the Horizon available in PDF, EPUB and Kindle. Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Genetically Modified Mosquitoes for Malaria Control
Genetically Modified Mosquitoes for Malaria Control - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Genetically Modified Mosquitoes for Malaria Control write by Christophe Boete. This book was released on 2006-07-15. Genetically Modified Mosquitoes for Malaria Control available in PDF, EPUB and Kindle. Despite a century of research and attempts to control one of the deadliest foes of mankind, the malaria situation remains a major public health problem. Obviously biological explanations (the resistance of parasites and mosquitoes against available drugs and insecticides respectively) are often given, but they remain partial and incomplete. Indeed,
Mosquito Gene Drives and the Malaria Eradication Agenda
Mosquito Gene Drives and the Malaria Eradication Agenda - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mosquito Gene Drives and the Malaria Eradication Agenda write by Rebeca Carballar-Lejarazú. This book was released on 2023-02-24. Mosquito Gene Drives and the Malaria Eradication Agenda available in PDF, EPUB and Kindle. Malaria is one of most serious infectious diseases today and has afflicted humankind for thousands of years. A significant number of people still die from this mosquito-borne disease, despite the use of various malaria prevention and control methods over hundreds of years and more than a century of coordinated global control efforts using modern tools, together with research into and development of new strategies for prevention, diagnosis, and disease treatment. Genetic approaches that focus on the vector mosquitoes to prevent malaria parasite transmission have been considered for many decades. Genetic control strategies received a significant boost with the successful development of gene drive systems, genetic methods for rapidly spreading beneficial genes and phenotypes through mosquito populations. This book reviews some concepts of gene drive systems and describes pioneering applications to control mosquito populations and prevent parasite transmission.
The Development of Gene Drives for Genetic Control of the Malaria Mosquito
The Development of Gene Drives for Genetic Control of the Malaria Mosquito - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Development of Gene Drives for Genetic Control of the Malaria Mosquito write by Andrew Marc Hammond. This book was released on 2016. The Development of Gene Drives for Genetic Control of the Malaria Mosquito available in PDF, EPUB and Kindle.
