Handbook of Pharmaceutical Salts Properties, Selection, and Use - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Handbook of Pharmaceutical Salts Properties, Selection, and Use write by P. Heinrich Stahl. This book was released on 2008-08-04. Handbook of Pharmaceutical Salts Properties, Selection, and Use available in PDF, EPUB and Kindle. This comprehensive up-to-date guide and information source is an instructive companion for all scientists involved in research and development of drugs and, in particular, of pharmaceutical dosage forms. The editors have taken care to address every conceivable aspect of the preparation of pharmaceutical salts and present the necessary theoretical foundations as well as a wealth of detailed practical experience in the choice of pharmaceutically active salts. Altogether, the contributions reflect the multidisciplinary nature of the science involved in selection of suitable salt forms for new drug products.
Solid-State Properties of Pharmaceutical Materials
Solid-State Properties of Pharmaceutical Materials - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Solid-State Properties of Pharmaceutical Materials write by Stephen R. Byrn. This book was released on 2017-07-12. Solid-State Properties of Pharmaceutical Materials available in PDF, EPUB and Kindle. Presents a detailed discussion of important solid-state properties, methods, and applications of solid-state analysis Illustrates the various phases or forms that solids can assume and discussesvarious issues related to the relative stability of solid forms and tendencies to undergo transformation Covers key methods of solid state analysis including X-ray powder diffraction, thermal analysis, microscopy, spectroscopy, and solid state NMR Reviews critical physical attributes of pharmaceutical materials, mainly related to drug substances, including particle size/surface area, hygroscopicity, mechanical properties, solubility, and physical and chemical stability Showcases the application of solid state material science in rational selection of drug solid forms, analysis of various solid forms within drug substance and the drug product, and pharmaceutical product development Introduces appropriate manufacturing and control procedures using Quality by Design, and other strategies that lead to safe and effective products with a minimum of resources and time
Early Drug Development, 2 Volume Set
Early Drug Development, 2 Volume Set - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Early Drug Development, 2 Volume Set write by Fabrizio Giordanetto. This book was released on 2018-12-10. Early Drug Development, 2 Volume Set available in PDF, EPUB and Kindle. This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final section focuses on intellectual property aspects during early clinical development. The emphasis throughout is on recent case studies to exemplify salient points, resulting in an abundance of practice-oriented information that is usually not available from other sources. Aimed at medicinal chemists in industry as well as academia, this invaluable reference enables readers to understand and navigate the challenges in developing clinical candidate molecules that can be successfully used in phase one clinical trials.
Handbook of Pharmaceutical Excipients
Handbook of Pharmaceutical Excipients - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Handbook of Pharmaceutical Excipients write by Raymond C. Rowe. This book was released on 2009-01-01. Handbook of Pharmaceutical Excipients available in PDF, EPUB and Kindle. An internationally acclaimed reference work recognized as one of the most authoritative and comprehensive sources of information on excipients used in pharmaceutical formulation with this new edition providing 340 excipient monographs. Incorporates information on the uses, and chemical and physical properties of excipients systematically collated from a variety of international sources including: pharmacopeias, patents, primary and secondary literature, websites, and manufacturers' data; extensive data provided on the applications, licensing, and safety of excipients; comprehensively cross-referenced and indexed, with many additional excipients described as related substances and an international supplier's directory and detailed information on trade names and specific grades or types of excipients commercially available.
The Handbook of Medicinal Chemistry
The Handbook of Medicinal Chemistry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Handbook of Medicinal Chemistry write by Andrew Davis. This book was released on 2015-07-07. The Handbook of Medicinal Chemistry available in PDF, EPUB and Kindle. Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.
