Heat Shock Proteins in Signaling Pathways

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Release : 2019
Genre : Biochemistry
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Book Rating : 530/5 ( reviews)

Heat Shock Proteins in Signaling Pathways - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Heat Shock Proteins in Signaling Pathways write by Alexzander A. A. Asea. This book was released on 2019. Heat Shock Proteins in Signaling Pathways available in PDF, EPUB and Kindle. This edited volume offers an insightful overview of contemporary research on signaling pathways. These signaling processes are the comprehensive mechanisms by which all cellular organisms communicate internally and externally with their microenvironment. The volume is focused on heat shock proteins (HSP), which are uniquely involved in a number of critical signaling pathways. Errors in signaling pathways and in the processing of cellular information are known to be responsible for the majority of diseases including cancer, inflammatory and neurological disorders. The knowledge gained from better understanding these mechanisms can help in elucidating disease processes and will assist in development and design of novel targeted treatment therapies to combat human diseases and disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Heat Shock Proteins in Cancer

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Release : 2007-09-09
Genre : Medical
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Book Rating : 012/5 ( reviews)

Heat Shock Proteins in Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Heat Shock Proteins in Cancer write by Stuart K. Calderwood. This book was released on 2007-09-09. Heat Shock Proteins in Cancer available in PDF, EPUB and Kindle. Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.

Plant Signaling Molecules

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Release : 2019-03-15
Genre : Technology & Engineering
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Book Rating : 522/5 ( reviews)

Plant Signaling Molecules - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Plant Signaling Molecules write by M. Iqbal R. Khan. This book was released on 2019-03-15. Plant Signaling Molecules available in PDF, EPUB and Kindle. Plant Signaling Molecule: Role and Regulation under Stressful Environments explores tolerance mechanisms mediated by signaling molecules in plants for achieving sustainability under changing environmental conditions. Including a wide range of potential molecules, from primary to secondary metabolites, the book presents the status and future prospects of the role and regulation of signaling molecules at physiological, biochemical, molecular and structural level under abiotic stress tolerance. This book is designed to enhance the mechanistic understanding of signaling molecules and will be an important resource for plant biologists in developing stress tolerant crops to achieve sustainability under changing environmental conditions. - Focuses on plant biology under stress conditions - Provides a compendium of knowledge related to plant adaptation, physiology, biochemistry and molecular responses - Identifies treatments that enhance plant tolerance to abiotic stresses - Illustrates specific physiological pathways that are considered key points for plant adaptation or tolerance to abiotic stresses

Molecular Chaperones in Health and Disease

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Release : 2005-09-27
Genre : Science
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Book Rating : 759/5 ( reviews)

Molecular Chaperones in Health and Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Chaperones in Health and Disease write by Matthias Gaestel. This book was released on 2005-09-27. Molecular Chaperones in Health and Disease available in PDF, EPUB and Kindle. Molecular chaperones are involved in a wide variety of essential cellular processes in living cells. A subset of molecular chaperones have been initially described as heat shock proteins protecting cells from stress damage by keeping cellular proteins in a folding competent state and preventing them from irreversible aggregation. Later it became obvious that molecular chaperones are also expressed constitutively in the cell and are involved in complex processes such as protein synthesis, intracellular protein transport, post-translational modification and secretion of proteins as well as receptor signalling. Hence, it is not surprising that molecular chaperones are implicated in the pathogenesis of many relevant diseases and could be regarded as potential pharmacological targets. Starting with the analysis of the mode of action of chaperones at the molecular, cellular and organismic level, this book will then describe specific aspects where modulation of chaperone action could be of pharmacological and therapeutic interest.

Inflammation, 4 Volume Set

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Release : 2018-02-20
Genre : Medical
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Book Rating : 993/5 ( reviews)

Inflammation, 4 Volume Set - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Inflammation, 4 Volume Set write by Jean-Marc Cavaillon. This book was released on 2018-02-20. Inflammation, 4 Volume Set available in PDF, EPUB and Kindle. Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.