Bioinformatics for High Throughput Sequencing

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Release : 2011-10-26
Genre : Science
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Book Rating : 826/5 ( reviews)

Bioinformatics for High Throughput Sequencing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Bioinformatics for High Throughput Sequencing write by Naiara Rodríguez-Ezpeleta. This book was released on 2011-10-26. Bioinformatics for High Throughput Sequencing available in PDF, EPUB and Kindle. Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.

High-Throughput Next Generation Sequencing

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Release : 2011-03-22
Genre : Medical
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Book Rating : 881/5 ( reviews)

High-Throughput Next Generation Sequencing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook High-Throughput Next Generation Sequencing write by Young Min Kwon. This book was released on 2011-03-22. High-Throughput Next Generation Sequencing available in PDF, EPUB and Kindle. Due to their novel concepts and extraordinary high-throughput sequencing capacity, the “next generation sequencing” methods allow scientists to grasp system-wide landscapes of the complex molecular events taking place in various biological systems, including microorganisms and microbial communities. These methods are now being recognized as essential tools for a more comprehensive and deeper understanding of the mechanisms underlying many biological processes. In High-Throughput Next Generation Sequencing: Methods and Applications, experts in the field explore the most recent advances in the applications of next generation sequencing technologies with an emphasis on microorganisms and their communities; however, the methods described in this book will also offer general applications relevant to the study of any living organisms. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, High-Throughput Next Generation Sequencing: Methods and Applications is an excellent collection of chapters to aid all scientists who wish to apply these innovative research tools to enhance their own pursuits in microbiology and also biology in general.

Next Generation Sequencing

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Release : 2016-01-14
Genre : Medical
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Book Rating : 401/5 ( reviews)

Next Generation Sequencing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Next Generation Sequencing write by Jerzy Kulski. This book was released on 2016-01-14. Next Generation Sequencing available in PDF, EPUB and Kindle. Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.

Next-Generation Sequencing Data Analysis

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Release : 2016-04-06
Genre : Mathematics
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Book Rating : 899/5 ( reviews)

Next-Generation Sequencing Data Analysis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Next-Generation Sequencing Data Analysis write by Xinkun Wang. This book was released on 2016-04-06. Next-Generation Sequencing Data Analysis available in PDF, EPUB and Kindle. A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi

Clinical Applications for Next-Generation Sequencing

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Release : 2015-09-10
Genre : Science
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Book Rating : 410/5 ( reviews)

Clinical Applications for Next-Generation Sequencing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Clinical Applications for Next-Generation Sequencing write by Urszula Demkow. This book was released on 2015-09-10. Clinical Applications for Next-Generation Sequencing available in PDF, EPUB and Kindle. Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. Fills the gap between state-of-the-art technology and evidence-based practice Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment Promotes a practical tool that clinicians can apply directly to patient care Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases Presents evidence regarding the important role of NGS in current diagnostic strategies