High-Throughput Screening in Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook High-Throughput Screening in Drug Discovery write by Jörg Hüser. This book was released on 2006-12-13. High-Throughput Screening in Drug Discovery available in PDF, EPUB and Kindle. Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results. For both academics and professionals in the pharma and biotech industries working on small molecule screening.
High Throughput Screening
High Throughput Screening - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook High Throughput Screening write by William P. Janzen. This book was released on 2002-04-18. High Throughput Screening available in PDF, EPUB and Kindle. In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.
High Throughput Screening
High Throughput Screening - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook High Throughput Screening write by John P. Devlin. This book was released on 1997-05-06. High Throughput Screening available in PDF, EPUB and Kindle. Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high
A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery
A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery write by Taosheng Chen. This book was released on 2019-08-30. A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery available in PDF, EPUB and Kindle. The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However, few scientists have the multidisciplinary experience needed to control all aspects of an HTS drug discovery project. A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery integrates the experience of diverse experts who offer fundamental and practical guidance across numerous situations. The book first discusses assay developments for important target classes such as protein kinases and phosphatases, proteases, nuclear receptors, G protein-coupled receptors, ion channels, and heat shock proteins. It next examines assay developments for cell viability, apoptosis, and infectious diseases. The contributors explore the application of emerging technologies and systems, including image-based high content screening, RNA interference, and primary cells. Finally, they discuss the essential components of the integrated HTS process, such as screening automation, compound library management, the screening of natural products from botanical sources, and screening informatics. Designed to motivate researchers to bring further advances to the field, this volume provides practical guidance on how to initiate, validate, optimize, and manage a bioassay intended to screen large collections of compounds. Drawing on the knowledge from experts actively involved in assay development and HTS, this is a resource that is both comprehensive and focused.
High-Throughput Screening for Drug Discovery
High-Throughput Screening for Drug Discovery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook High-Throughput Screening for Drug Discovery write by Shailendra K. Saxena. This book was released on 2022-05-25. High-Throughput Screening for Drug Discovery available in PDF, EPUB and Kindle. The book focuses on various aspects and properties of high-throughput screening (HTS), which is of great importance in the development of novel drugs to treat communicable and non-communicable diseases. Chapters in this volume discuss HTS methodologies, resources, and technologies and highlight the significance of HTS in personalized and precision medicine.
