Hippocampal Microcircuits

Download Hippocampal Microcircuits PDF Online Free

Author :
Release : 2010-02-01
Genre : Medical
Kind :
Book Rating : 966/5 ( reviews)

Hippocampal Microcircuits - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hippocampal Microcircuits write by Vassilis Cutsuridis. This book was released on 2010-02-01. Hippocampal Microcircuits available in PDF, EPUB and Kindle. Rich in detail, Hippocampal Microcircuits: A Computational Modeler’s Resource Book provides succinct and focused reviews of experimental results. It is an unparalleled resource of data and methodology that will be invaluable to anyone wishing to develop computational models of the microcircuits of the hippocampus. The editors have divided the material into two thematic areas. Covering the subject’s experimental background, leading neuroscientists discuss the morphological, physiological and molecular characteristics as well as the connectivity and synaptic properties of the various cell types found in the hippocampus. Here, ensemble activity, related to behavior, on the part of morphologically identified neurons in anesthetized and freely moving animals, lead to insights into the functions of hippocampal areas. In the second section, on computational analysis, computational neuroscientists present models of hippocampal microcircuits at various levels of detail, including single-cell and network levels. A full chapter is devoted to the single-neuron and network simulation environments currently used by computational neuroscientists in developing their models. In addition to the above, the chapters also identify outstanding questions and areas in need of further clarification that will guide future research by computational neuroscientists.

Handbook of Brain Microcircuits

Download Handbook of Brain Microcircuits PDF Online Free

Author :
Release : 2018
Genre : Medical
Kind :
Book Rating : 114/5 ( reviews)

Handbook of Brain Microcircuits - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Handbook of Brain Microcircuits write by Gordon M. Shepherd. This book was released on 2018. Handbook of Brain Microcircuits available in PDF, EPUB and Kindle. In order to focus on principles, each chapter in this work is brief, organized around 1-3 wiring diagrams of the key circuits, with several pages of text that distil the functional significance of each microcircuit

Structure, function, and plasticity of hippocampal dentate gyrus microcircuits

Download Structure, function, and plasticity of hippocampal dentate gyrus microcircuits PDF Online Free

Author :
Release : 2015-02-13
Genre : Neurosciences. Biological psychiatry. Neuropsychiatry
Kind :
Book Rating : 87X/5 ( reviews)

Structure, function, and plasticity of hippocampal dentate gyrus microcircuits - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Structure, function, and plasticity of hippocampal dentate gyrus microcircuits write by Peter Jonas. This book was released on 2015-02-13. Structure, function, and plasticity of hippocampal dentate gyrus microcircuits available in PDF, EPUB and Kindle. The hippocampus mediates several higher brain functions, such as learning, memory, and spatial coding. The input region of the hippocampus, the dentate gyrus, plays a critical role in these processes. Several lines of evidence suggest that the dentate gyrus acts as a preprocessor of incoming information, preparing it for subsequent processing in CA3. For example, the dentate gyrus converts input from the entorhinal cortex, where cells have multiple spatial fields, into the spatially more specific place cell activity characteristic of the CA3 region. Furthermore, the dentate gyrus is involved in pattern separation, transforming relatively similar input patterns into substantially different output patterns. Finally, the dentate gyrus produces a very sparse coding scheme in which only a very small fraction of neurons are active at any one time. How are these unique functions implemented at the level of cells and synapses? Dentate gyrus granule cells receive excitatory neuron input from the entorhinal cortex and send excitatory output to the hippocampal CA3 region via the mossy fibers. Furthermore, several types of GABAergic interneurons are present in this region, providing inhibitory control over granule cell activity via feedback and feedforward inhibition. Additionally, hilar mossy cells mediate an excitatory loop, receiving powerful input from a small number of granule cells and providing highly distributed excitatory output to a large number of granule cells. Finally, the dentate gyrus is one of the few brain regions exhibiting adult neurogenesis. Thus, new neurons are generated and functionally integrated throughout life. How these specific cellular and synaptic properties contribute to higher brain functions remains unclear. One way to understand these properties of the dentate gyrus is to try to integrate experimental data into models, following the famous Hopfield quote: “Build it, and you understand it.” However, when trying this, one faces two major challenges. First, hard quantitative data about cellular properties, structural connectivity, and functional properties of synapses are lacking. Second, the number of individual neurons and synapses to be represented in the model is huge. For example, the dentate gyrus contains ~1 million granule cells in rodents, and ~10 million in humans. Thus, full scale models will be complex and computationally demanding. In this Frontiers Research Topic, we collect important information about cells, synapses, and microcircuit elements of the dentate gyrus. We have put together a combination of original research articles, review articles, and a methods article. We hope that the collected information will be useful for both experimentalists and modelers. We also hope that the papers will be interesting beyond the small world of “dentology,” i.e., for scientists working on other brain areas. Ideally, the dentate gyrus may serve as a blueprint, helping neuroscientists to define strategies to analyze network organization of other brain regions.

Artificial Neural Networks - ICANN 2010

Download Artificial Neural Networks - ICANN 2010 PDF Online Free

Author :
Release : 2010-09-03
Genre : Computers
Kind :
Book Rating : 188/5 ( reviews)

Artificial Neural Networks - ICANN 2010 - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Artificial Neural Networks - ICANN 2010 write by Konstantinos Diamantaras. This book was released on 2010-09-03. Artificial Neural Networks - ICANN 2010 available in PDF, EPUB and Kindle. This three volume set LNCS 6352, LNCS 6353, and LNCS 6354 constitutes the refereed proceedings of the 20th International Conference on Artificial Neural Networks, ICANN 2010, held in Thessaloniki, Greece, in September 2010. The 102 revised full papers, 68 short papers and 29 posters presented were carefully reviewed and selected from 241 submissions. The first volume is divided in topical sections on ANN applications, Bayesian ANN, bio inspired – spiking ANN, biomedical ANN, computational neuroscience, feature selection/parameter identification and dimensionality reduction, filtering, genetic – evolutionary algorithms, and image – video and audio processing.

The Hippocampus Book

Download The Hippocampus Book PDF Online Free

Author :
Release : 2024-11
Genre : Medical
Kind :
Book Rating : 32X/5 ( reviews)

The Hippocampus Book - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Hippocampus Book write by Richard Morris. This book was released on 2024-11. The Hippocampus Book available in PDF, EPUB and Kindle. Known to be important for memory, the hippocampus has long been a prime focus for neuroscience research. This second edition of The Hippocampus Book is written by experts in a wide range of disciplines, with new chapters summarizing how disorders of hippocampal function contribute to neurological and psychiatric conditions. The editors draw on their experience in hippocampal anatomy, physiology, cognitive neuroscience and disease pathobiology to weave together an authoritative book which will interest those working in numerous neuroscientific disciplines.