Hormones, Cognition and Dementia - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hormones, Cognition and Dementia write by Eef Hogervorst. This book was released on 2009-09-24. Hormones, Cognition and Dementia available in PDF, EPUB and Kindle. Basic and clinical research on sex steroids, ageing, and cognition to integrate existing findings with emerging data.
Hormone Therapy and the Brain
Hormone Therapy and the Brain - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hormone Therapy and the Brain write by Victor W. Henderson. This book was released on 1999-10-15. Hormone Therapy and the Brain available in PDF, EPUB and Kindle. Written by an acknowledged leader in the field, this is a vital clinical reference on the influence of estrogen replacement therapy on Alzheimer's disease, visual dementia, stroke, disorders of movement, epilepsy, migraine headache, and multiple sclerosis. It opens with introductory information and an overview of estrogen and the brain and with coverage of the mechanisms of estrogen action on the brain and the neuroprotective effects of estrogen. Two sections cover the effects of estrogen replacement therapy on mood behavior and cognition and a major section focuses on Alzheimer's disease and other dementias. Another key section covers other neurological disorders, including stroke prevention after menopause, stroke protection in men, neuroprotection after stroke, movement disorders, epilepsy, migraine headache, and multiple sclerosis. Includes color illustrations, bibliographic references and index.
Hormone Replacement Therapy and Cognition
Hormone Replacement Therapy and Cognition - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Hormone Replacement Therapy and Cognition write by U. S. Department of Health and Human Services. This book was released on 2013-06-28. Hormone Replacement Therapy and Cognition available in PDF, EPUB and Kindle. In this systematic evidence review, we evaluate data on the use of hormone replacement therapy (HRT) to prevent cognitive decline and dementia in healthy postmenopausal women. Specifically, we reviewed the literature reporting effects of HRT on cognitive function in women without dementia. In addition, we conducted a review and meta-analysis of studies of HRT and dementia, focusing on Alzheimer disease. Results of this review have been recently published. This report is part of a larger project on the risks and benefits of HRT prepared for the U.S. Preventive Services Task Force to assist them in making recommendations. Between 3 and 8 million people in the United States have dementia. The most common type of dementia is Alzheimer disease, which affects 3 to 4 million people and is the fourth leading cause of death in the United States. The incidence of dementia is 1 percent per year in older individuals, although in the most elderly populations this rate may be as high as 2 to 3 percent. One community-based prevalence study in east Boston estimated that almost 50 percent of those aged 85 and over suffered from dementia. Most studies report that after accounting for differences in life expectancy, women have a 1.4 to 3-fold higher risk of Alzheimer disease than men. The life expectancy of demented patients is greatly reduced. Those with early-onset (before age 60) Alzheimer disease have a median survival of 6.7 to 8.1 years, while survival in those with late-onset disease is 4.8 to 6.0 years. In 1991, the annual cost of Alzheimer disease was estimated to be $67.3 billion. Given the expected growth of the elderly population, this financial cost, as well as the emotional and physical costs of caring for demented patients, will continue to increase. Observational data suggest a possible but inconsistent relationship between endogenous estrogen exposure and cognition. Women in the high estrogen phase of the menstrual cycle have been shown to perform better on tests of motor skills compared to when they are in the low estrogen phase of the cycle. Bone mineral density, hypothesized to be a marker of cumulative estrogen exposure, has been correlated with risk of cognitive deterioration. Because of the association between endogenous estrogen exposure and cognition, it can be hypothesized that hormone replacement therapy (HRT) after menopause may prevent cognitive decline and the development of dementia.
Neurodegeneration and Alzheimer's Disease
Neurodegeneration and Alzheimer's Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Neurodegeneration and Alzheimer's Disease write by Ralph N. Martins. This book was released on 2019-07-10. Neurodegeneration and Alzheimer's Disease available in PDF, EPUB and Kindle. Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.
The Effects of Estrogen on Brain Function
The Effects of Estrogen on Brain Function - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Effects of Estrogen on Brain Function write by Natalie L. Rasgon. This book was released on 2006-05-05. The Effects of Estrogen on Brain Function available in PDF, EPUB and Kindle. This timely volume reviews current data on the effects of estrogen on the central nervous system, highlighting clinical aspects of this topic. Experts from the fields of psychiatry, pharmacology, neurology, and geriatrics collaborate to clarify the known risks and benefits of hormone therapy and explore questions that remain to be elucidated. Among the topics discussed: " Preclinical data on estrogen's effects on cognitive performance " The short-lived effects of hormone replacement therapy on cognitive function " Structural and functional brain imaging data regarding estrogen's effects on the central nervous system " Preclinical efforts to develop effective NeuroSERMs for the brain " The effects of estrogen on mood Citing the ongoing confusion over the risks and benefits of estrogen therapy, the contributors emphasize the need for additional research on medication, doses, preparations, methods of administration, alternative therapies, and supplements. This volume educates researchers, clinicians, and students on the current knowledge—including the effects of estrogen on mood, cognition, and brain metabolism—and provides guidelines for clinical practice and future research. Contributors: Roberta Diaz Brinton, Ph.D., University of Southern California; Cheri L. Geist, B.A., David Geffen School of Medicine, University of California at Los Angeles; Robert B. Gibbs, Ph.D., University of Pittsburgh School of Pharmacy; Eva Hogervorst, Ph.D., University of Loughborough and University of Oxford; Pauline M. Maki, Ph.D., Neuropsychiatric Institute, University of Illinois–Chicago; Peter J. Schmidt, M.D., National Institute of Mental Health; Daniel H. S. Silverman, M.D., Ph.D., David Geffen School of Medicine, University of California at Los Angeles; Katherine E. Williams, M.D., Stanford University School of Medicine; Kristine Yaffe, M.D., University of California, San Francisco, and San Francisco VA Medical Center; Laurel N. Zappert, B.A., Stanford University School of Medicine; Liqin Zhao, Ph.D., University of Southern California
