How the Immune System Recognizes Self and Nonself

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Release : 2008-04-08
Genre : Medical
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Book Rating : 843/5 ( reviews)

How the Immune System Recognizes Self and Nonself - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook How the Immune System Recognizes Self and Nonself write by Daisuke Kitamura. This book was released on 2008-04-08. How the Immune System Recognizes Self and Nonself available in PDF, EPUB and Kindle. How do you discriminate yourself from other people? This question must sound odd to you since you easily recognize others at a glance and, without any effort, would not mistake them for yourself. However, it is not always easy for some people to discriminate themselves from others. For example, patients with schi- phrenia often talk with “others” living inside themselves. Thus it is likely that n- mally your brain actively recognizes and remembers the information belonging to yourself and discriminates it from the information provided by others, although you are not conscious of it. This brain function must have been particularly important for most animals to protect their lives from enemies and for species to survive through evolution. Similarly, higher organisms have also acquired their immune system through evolution that discriminates nonself pathogens and self-body to protect their lives from pathogens such as bacteria or viruses. The brain system may distinguish integrated images of self and nonself created from many inputs, such as vision, sound, smell, and others. The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything but self: for example, bacteria, viruses, toxins, pollens, chemicals, transplanted organs, and even tumor cells derived from self-tissue. To this end the immune system recruits different kinds of immune cells, such as B and T lymphocytes, natural killer (NK) cells, dendritic cells, and macrophages.

Molecular Biology of The Cell

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Release : 2002
Genre : Cytology
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Book Rating : 183/5 ( reviews)

Molecular Biology of The Cell - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of The Cell write by Bruce Alberts. This book was released on 2002. Molecular Biology of The Cell available in PDF, EPUB and Kindle.

Janeway's Immunobiology

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Release : 2010-06-22
Genre : Medical
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Book Rating : 575/5 ( reviews)

Janeway's Immunobiology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Janeway's Immunobiology write by Kenneth Murphy. This book was released on 2010-06-22. Janeway's Immunobiology available in PDF, EPUB and Kindle. The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

A Historical Perspective on Evidence-Based Immunology

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Release : 2015-11-25
Genre : Medical
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Book Rating : 754/5 ( reviews)

A Historical Perspective on Evidence-Based Immunology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook A Historical Perspective on Evidence-Based Immunology write by Edward J. Moticka. This book was released on 2015-11-25. A Historical Perspective on Evidence-Based Immunology available in PDF, EPUB and Kindle. A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells

Military Strategies for Sustainment of Nutrition and Immune Function in the Field

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Release : 1999-05-13
Genre : Medical
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Book Rating : 183/5 ( reviews)

Military Strategies for Sustainment of Nutrition and Immune Function in the Field - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Military Strategies for Sustainment of Nutrition and Immune Function in the Field write by Institute of Medicine. This book was released on 1999-05-13. Military Strategies for Sustainment of Nutrition and Immune Function in the Field available in PDF, EPUB and Kindle. Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.