Ibuprofen: Pharmacology, Therapeutics and Side Effects

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Release : 2013-02-01
Genre : Medical
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Book Rating : 962/5 ( reviews)

Ibuprofen: Pharmacology, Therapeutics and Side Effects - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ibuprofen: Pharmacology, Therapeutics and Side Effects write by K. D. Rainsford. This book was released on 2013-02-01. Ibuprofen: Pharmacology, Therapeutics and Side Effects available in PDF, EPUB and Kindle. Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.

Ibuprofen

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Release : 2003-09-02
Genre : Medical
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Book Rating : 586/5 ( reviews)

Ibuprofen - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ibuprofen write by Kim D. Rainsford. This book was released on 2003-09-02. Ibuprofen available in PDF, EPUB and Kindle. Ibuprofen is widely used throughout the world for a variety of conditions. This reference work provides a comprehensive and critical review of the basic science and clinical aspects of the drug. The book begins with the history and development of the drug and its current patterns of use world- wide before moving on to examine its basic pharmaceutical attributes and medicinal chemistry. The properties of various formulations are described (oral prescription and OTC, topical and others) are described. The pharmacokinetics of ibuprofen in animals and humans is discussed - highlighting the factors affecting absorption, distribution, metabolism and elimination. The clinical pharmacology and toxicology and the drug's mechanisms of action in different disease states and conditions are covered. The therapeutic uses in various acute and inflammatory conditions is detailed. Also considered are the safety versus efficacy issues and the pharmacoepidemiological data.

Ibuprofen

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Release : 2015-06-25
Genre : Medical
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Book Rating : 601/5 ( reviews)

Ibuprofen - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ibuprofen write by K. D. Rainsford. This book was released on 2015-06-25. Ibuprofen available in PDF, EPUB and Kindle. Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and inflammatory conditions. It has also been widely investigated for application in a variety of painful and non-pain inflammatory states including cancer and neurodegenerative conditions, reflecting the unique and novel properties of the drug that would never have been foreseen from knowledge of the properties when it was initially discovered. Edited by leading world expert with over 40 years record in research, teaching and as a scientific advisor in the field of anti-inflammatory/analgesic agents. Professor Kim Rainsford is also the founding Editor-in-Chief of the journal, Inflammopharmacology, as well as being an Associate Editor of The Journal of Pharmacy & Pharmacology. Provides a thorough coverage of the medicinal chemistry and pharmaceutics of ibuprofen, and its pharmacokinetics in both humans and animals. Includes molecular, pharmacological and toxicological studies, and discusses the safety and efficacy of non-prescription ibuprofen, including its side effects. Ibuprofen: Discovery, Development & Therapeutics provides a definitive reference on all the main aspects of the chemical and pharmaceutical properties, mechanisms of action and therapeutic uses of ibuprofen including its role in the prevention and treatment of rheumatic conditions, cancer and neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases. The book has its origins in a volume first published in 1999, since when there have been considerable advances in research and clinical studies on ibuprofen in the treatment of many inflammatory and even non-inflammatory states. This book will prove invaluable to scientists, clinicians, pharmacists and all those who need to know about the actions and uses of anti-inflammatory and analgesic drugs.

Ibuprofen

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Release : 2014-05-14
Genre : Medical
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Book Rating : 606/5 ( reviews)

Ibuprofen - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ibuprofen write by Brown Brant R Carter Wilton C. This book was released on 2014-05-14. Ibuprofen available in PDF, EPUB and Kindle. In this book, the authors present topical research in the study of the clinical pharmacology, medical uses, and adverse effects of ibuprofen. Topics discussed include the occurrence, ecotoxicity and water remediation technologies of ibuprofen in the aquatic environment; associated adverse drug reaction in ibuprofen use; hybrid multifunctional ibuprofen drugs; a pharmaceutical nanotechnology approach to ibuprofen delivery; vibrational dynamics and chiral properties of racemate and pure enantiomers of ibuprofen complexed in cyclodextrins; therapeutic effects of ibuprofen on transgenic mice models of neurodegenerative diseases; and the use of ibuprofen for pain relief in gynecology.

Drug-Induced Liver Injury

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Release : 2019-07-13
Genre : Medical
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Book Rating : 173/5 ( reviews)

Drug-Induced Liver Injury - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drug-Induced Liver Injury write by . This book was released on 2019-07-13. Drug-Induced Liver Injury available in PDF, EPUB and Kindle. Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series