Immune-mediated Disorders of the Central Nervous System in Children - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immune-mediated Disorders of the Central Nervous System in Children write by Lucia Angelini. This book was released on 2002. Immune-mediated Disorders of the Central Nervous System in Children available in PDF, EPUB and Kindle. Immunopathogenesis has recently been receiving increased interest from researchers, leading to a better understanding of the mechanisms of neurological disorders and consequently to new diagnostic approaches and therapeutic perspectives. Clinical neuroimmunology in childhood is the focus of the present volume. This book is divided into three sections. The first part deals with the relationship between the immune and the nervous systems, from antigen presentation to autoimmunity and its role in neurological disease. In the second part, the nosography of immune-mediated neurological diseases in children is described, including those primarily involving the central nervous system and those secondary to systemic immunological disorders. The last part of the book is devoted to diagnostic and therapeutic criteria.
Multiple Sclerosis in Childhood
Multiple Sclerosis in Childhood - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Multiple Sclerosis in Childhood write by Martino Ruggieri. This book was released on 2010-05-01. Multiple Sclerosis in Childhood available in PDF, EPUB and Kindle. There are still many unresolved questions concerning MS in children. This unique work provides the reader with a complete update in paediatric neuroimmunology. There is coverage of neglected topics and rare conditions occurring in the youngest patients.
Inflammatory and Autoimmune Disorders of the Nervous System in Children
Inflammatory and Autoimmune Disorders of the Nervous System in Children - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Inflammatory and Autoimmune Disorders of the Nervous System in Children write by Russell C. Dale. This book was released on 2010-01-19. Inflammatory and Autoimmune Disorders of the Nervous System in Children available in PDF, EPUB and Kindle. Inflammatory disorders of the nervous system, although individually uncommon, collectively make up 10-20% of acute paediatric neurology presentations and many are potentially treatable. Research into them is lagging behind adult research, but better diagnosis and often simple treatments could lead to substantial clinical benefit and reduction in long-term disability. This book provides a detailed and comprehensive summary of the childhood diseases that are, or are likely to be, caused by the immune system. The authors not only describe these disorders and their treatments comprehensively, helping pediatricians and pediatric neurologists to improve their understanding and recognition of the conditions, but also highlight recent and exciting developments that will be of considerable importance in the future.
Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics
Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics write by Emmanuelle Waubant. This book was released on 2017-11-07. Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics available in PDF, EPUB and Kindle. This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.
Induction of Central Nervous System Disease by the Adaptive Immune Response
Induction of Central Nervous System Disease by the Adaptive Immune Response - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Induction of Central Nervous System Disease by the Adaptive Immune Response write by Robert Weissert. This book was released on 2017-11-23. Induction of Central Nervous System Disease by the Adaptive Immune Response available in PDF, EPUB and Kindle. Over the last years it has become evident that many neurological diseases of the central nervous system (CNS) are induced by a specific adaptive immune response directed against molecules expressed on CNS-resident cells. Well-recognized examples are anti-N-Methyl-D-Aspartate Receptor (NMDAR) encephalitis which is characterized by the presence of antibodies against neuron-expressed NMDAR, or neuromyelitis optica (NMO), induced by antibodies to astrocyte-expressed aquaporin-4. Many more examples exist, and antibodies, and T or/and B cells have increasingly been associated with CNS disease. Often the symptoms of these diseases have not been typically reported to have an immune aetiology. Beside classical neurological symptoms like ataxia, vision disturbance, and motor or sensory symptoms, these can include cognitive disturbances, behavioral abnormalities, or/and epileptic seizures. Although much has been learned regarding the pathophysiology of prototypic examples of these disorders, there are still major gaps in our understanding of their biology. This may be due to the fact that they are rare diseases, and their therapies are still very limited. This research topic includes contributions addressing the analysis of the adaptive immune response driving disease including target antigens, molecular epitope mapping, and factors involved in the disease pathogenesis such as complement activation cascades, genetic and genomic regulation, as well as environmental triggers. Diagnostic criteria and methods, and treatment are also discussed. The overall aim of the volume is to review progress in our pathophysiological understanding of immune-mediated CNS disorders in order to advance diagnostic and therapeutic approaches, and ultimately improve outcomes for patients.
